2017-10-202017-10-201997CHAVES, Nilo Sérgio Trancoso; BARROS, Paulo Sérgio de Moraes; MARTINS, Apóstolo Ferreira; ARAÚJO, Eugênio Gonçalves de; EURIDES, Duvaldo; ARAÚJO, Larissa Franco de; JACOMINI, Clausmir Zanetti. O cão (Canis familiaris) como unidade experimental para as ceratoplastias xenógenas. Veterinária Notícias, Uberlândia, v. 3, n. 1, p. 95-97, 1997.e- 1983-0777http://repositorio.bc.ufg.br/handle/ri/12633Twenty mixed breed dogs, with a 1 O kg average weight, were divided into two groups and received swine cornea penetrating xenografts. The dogs from Group 1 were treated with 2% cyclosporin and gentamicin sulfate in the form of eye drops. The animais from Group 2 were treated with corticosteroids and gentamicin sulfate eye drops. After surgery each animal had a head protector, resembling an E-collar, installed. Of Group 1, ali ten dogs finished the triai alive and without impairing the implant. ln Group 2, five dogs finished the triai alive, three dogs were sacrificed between days 14 and 21 PO, due to corticosteroid side effects. These dogs, however, did not interfere with the grafts. Two of the animais hurt themselves, impairing the grafts, and had to be sacrificed. The dogs did not try to get out of the cage frequently, had good hygiene and feeding discipline and could stand multiple barbituate anesthesis. Additionally, due to the large number of abandoned dogs on the streets, there are animais available that can be used for experiments, respecting the rules of animal protection. Although two animais (10%) destroyed the graft, dogs were found to be useful experimental units. This contradicts the opinion of many researchers who prefer rabbits or chickens as cornea receptors.porAcesso AbertoCaninoSuínoXenotransplanteCórneaCanineSwineXenotransplantCorneaArtigo