2023-06-292023-06-292017OLIVEIRA, Leandra A. R. et al. Isolation and structural characterization of two new furanoditerpenes from Pterodon emarginatus (Fabaceae). Journal of the Brazilian Chemical Society, Campinas, v. 28, n. 10, p. 1911-1917, 2017. DOI: 10.21577/0103-5053.20170029. Disponível em: https://s3.sa-east-1.amazonaws.com/static.sites.sbq.org.br/jbcs.sbq.org.br/pdf/2016-0749AR.pdf. Acesso em: 21 jun. 2023.e- 1678-47900103-5053http://repositorio.bc.ufg.br/handle/ri/22820A furanoditerpene-enriched fraction was obtained from the fruits of Pterodon emarginatus and submitted to semipreparative high performance liquid chromatography (HPLC). Two new furanoditerpenes, 6α,19β-diacetoxy-7β,14β-dihydroxyvouacapan and 6α-acetoxy7β,14β-dihydroxyvouacapan, in addition to the known compound methyl 6α-acetoxy7β-hydroxyvouacapan-17β-oate were obtained. Compound structures were determined by 1D and 2D nuclear magnetic resonance (NMR) experiments and electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry (ESI-FTICR-MS). The major compound methyl 6α-acetoxy-7β-hydroxyvouacapan-17β-oate was evaluated against promastigote forms of Leishmania amazonensis and L. braziliensis, presenting the concentration which causes lysis on 50% of parasites IC50 < 30 µg mL-1.engAcesso AbertoPterodonFuranoditerpenesVouacapanLeishmaniaArtigo10.21577/0103-5053.20170029