2024-02-262024-02-262023-08-10RIBEIRO, Cibele; VIANA, Narielly. Revisão da literatura sobre o impacto da estimulação da microbiota intestinal com prebióticos e probióticos na integridade cutânea. 2023. 31 f. Trabalho de Conclusão de Curso (Bacharelado em Farmácia) - Faculdade de Farmácia, Universidade Federal de Goiás, Goiânia, 2023.http://repositorio.bc.ufg.br//handle/ri/24411The manifestation of skin diseases is favored by several factors, among which are: genetic, environmental, psychosocial, and immunological. Considered a key regulator of the immune system, the microbiota acts in gut homeostasis. Changes in the microbiota can contribute to the development of several disease states, including diseases of the integumentary system. Aim: To analyze and present the effects of oral probiotics and prebiotics on the intestinal microbiota and their effects on the maintenance of sq1 kin characteristics, to improve the quality of life of a relevant portion of the world's population that suffers from skin problems. Method: The PubMed, Scielo and CAPES Periodicals Portal database from 2007 to 2023 was used with the following descriptors: “probiotics”, “prebiotics” “skin”, “intestinal microbiota”, “skin care” and “Skin microbiota”. The selected articles were read in full to develop the narration. Results: A healthy balance of gut microbiota is necessary for optimal skin health, resulting in metabolic and immune homeostasis, according to this narrative review. More research has linked changes in gut microbiota composition to the worsening of inflammatory skin conditions such as eczema and psoriasis. Any alteration in the diversity of intestinal microorganisms (dysbiosis) can make the host more vulnerable and interrupt the immune tolerance of the mucosa, influencing the health of the skin. As a result, a variety of dermatological conditions have been linked to intestinal dysbiosis. In the case of dysbiosis, probiotics and prebiotics should be used. Conclusion: Oral probiotics and prebiotics are beneficial in the clinical treatment of skin diseases involving immunological, inflammatory and dysbiotic factors in most of the studies addressed. Both probiotics and prebiotics can help you achieve a healthy complexion while alleviating existing skin conditions. Try them out by incorporating them into your daily skincare routine as well as your diet.porAcesso AbertoEixo intestino-peleMicrobioma da peleMicrobiota intestinalPrebióticosProbióticosGut-skin axisGut microbiotaPrebioticsProbioticsSkin microbiomeTrabalho de conclusão de curso de graduação (TCCG)