2013-10-262013-10-262009RIBEIRO, Vivian; VIEIRA, Iara Lúcia Barbosa Fernandes; PASSOS, Débora Cristina Silva dos; SILVA, Elayne Miguel da; VALE, Camila Regina do; FELÍCIO, Leandro Prado; FERREIRA, Heleno Dias; VIEIRA, Pabline Marinho; CARVALHO, Salvador de. Ausência de mutagenicidade de Solanum paniculatum L. em células somáticas de Drosophila melanogaster: SMART/asa. Revista de Biologia Neotropical, v. 6, n. 2, p. 27-33, 2009. Disponível em: <http://www.revistas.ufg.br/index.php/RBN/article/view/12851/8439>.1807-9652e-2178-0579http://repositorio.bc.ufg.br/handle/ri/1501v. 6, n. 2, p. 27-33, 2009.The lyophilized aqueous extract of Solanum paniculatum L. (jurubeba) leaves, a medicinal plant widely used by people as diuretic, in liver and spleen treatments, against fever and inflammation, underwent the SMART/wing test in somatic cells of Drosophila melanogaster for the evaluation of its mutagenic potential. We used three different concentrations of the leaf extract (2.5 mg.mL-1, 6.25 mg.mL-1, and 10 mg.mL-1), doxorubicin (DXR) as positive control, and distilled water with 5% sucrose as negative control. We employed three lineages of Drosophila in this experiment, flr³, ORR, and mwh. The larvae derived from the standard cross (ST: flr³ females x mwh males) and the high bioactivation cross (HB: ORR females x mwh males) were chronically treated and the wings of the emerging adults were analyzed. Our results showed no mutagenic activity of S. paniculatum L. ST or HB crosses.pt-BRDrosophila melanogasterGenotoxicidadeJurubebaSMART/asaSolanum paniculatum L.Article