2018-06-152018-06-152004OLIVEIRA, Cecília . M. A de et al. Chemical composition and antifungal activity of the essential oil of hyptis ovalifolia benth. (Lamiaceae). Journal of the Brazilian Chemical Society, Campinas, v. 15, n. 5, p. 756-759, 2004.0103-5053e- 1678-4790http://repositorio.bc.ufg.br/handle/ri/15277The leaves of Hyptis ovalifolia Benth. (Lamiaceae) were subjected to hydrodistillation and the resulting volatiles were investigated by GC/MS. The main constituent representing 60% of the essential oil was isolated by column chromatography and identified by spectroscopic methods as (R)-6-[(Z)-1-heptenyl]-5,6-dihydro-2H-pyran-2-one (1). This compound showed strong in vitro activity against four dermatophyte fungi Microsporum canis, Microsporum gypseum, Tricophyton mentagrophytes, and Tricophyton rubrum (a total of 60 strains) with a minimal inhibitory concentration observed in the range of 125-7.8 μg mL-1.engAcesso AbertoHyptis ovalifoliaEssential oilAntifungal activityLamiaceae(R)-6-[(Z)-1-heptenyl]- 5,6-dihydro-2H-pyran-2-oneArtigo