2024-08-302024-08-302024-07-04PIAI, Ricardo Figueiredo Paro; SILVA, Rômulo Freire Gomes; OLIVEIRA, Thalles Pires de. Associação entre diabetes mellitus e capsulite adesiva: uma revisão sistemática e meta-análise. 2024. 32 f. Trabalho de Conclusão de Curso (Bacharelado em Medicina) - Faculdade de Medicina, Universidade Federal de Goiás, Goiânia, 2024.http://repositorio.bc.ufg.br//handle/ri/25401Adhesive Capsulitis (AC) is a progressive painful condition associated with a gradual reduction in the range of motion of the shoulder joint, being associated with factors such as Diabetes Mellitus (DM). DM is a metabolic disorder that can damage connective tissues, including the shoulder joint capsule, increasing the risk of developing CA. Brazil, with a high prevalence of DM, faces a significant number of CA cases. The results can provide important insights into the clinical management of these patients. This review aims to analyze the relationship between adhesive capsulitis and diabetes mellitus, considering sex, dyslipidemia and glycemic control as possible influencers. The present systematic review was carried out in the Scopus, Embase and PubMed databases until April 2024. Observational studies were included, without time limitations, that evaluated risk factors for CA. This study used the PECOT criteria and converted them into Medical Subject Headings (MeSH) terms to investigate the relationship between adhesive capsulitis and diabetes. The terms "frozen shoulder" OR "adhesive capsulitis", "shoulder", "diabetes" OR "diabetes mellitus" OR "diabetic", and "risk factors" OR "risk" were used, combined by the Boolean operator "AND" in their variations in the English language. Articles outside the scope of the topic, incomplete articles and articles in languages other than English were excluded from the study. This study presents three retrospective cohort studies, totaling 3,812,635 participants. Our study demonstrated that patients with DM2 are associated with a higher chance of developing CA compared to patients without DM2 (OR 2.17; 95% [CI] = 1.32 to 3.56; p = 0.002). Multivariate analysis indicated that individuals with DM2 were more likely to develop CA than those without DM2 (HR 1.46; 95% [CI] = 1.33 to 1.61; p < 0.00001). Dyslipidemia was also associated with an increased risk of AC in patients with T2DM (HR 1.37; 95% [CI] = 1.24 to 1.51; p < 0.00001). Furthermore, women had a higher risk of developing AC compared to men (HR 1.44; 95% [CI] = 1.23 to 1.69; p < 0.00001). A correlation was also observed between lack of glycemic control and the development of CA. In conclusion, this study highlights the strong association between T2DM, dyslipidemia, female sex and CA, emphasizing the importance of strict metabolic control and adequate management of dyslipidemia in patients with T2DM to prevent or minimize the risk of developing CA. Future prospective, randomized controlled studies are needed to confirm these findings and elucidate the mechanisms underlying this association.porAcesso AbertoOmbro congeladoCapsulite adesivaDiabetes mellitusFatores de riscoFrozen shoulderAdhesive capsulitisDiabetes mellitusRisk factorsTrabalho de conclusão de curso de graduação (TCCG)