Imunomarcação de leishmania sp. e aspectos histológicos na terceira pálpebra de cães naturalmente infectados por leishmania (leishmania) chagasi
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Data
2015-08-14
Título da Revista
ISSN da Revista
Título de Volume
Editor
Jose Henrique Stringhini
Resumo
Canine visceral leishmaniasis (CVL) is a disease with multisystemic injuries, and among the various
tissues affected, the third eyelid (TE) is often involved. This ocular adnexa has been studied for the
leishmaniasis pathogenesis elucidation and for diagnosis advance. This study aimed to carry out the
parasite immunodetection and evaluate histologic lesions in TE of Leishmania (leishmania) chagasi
naturally infected dogs. Twenty-six TE samples from infected dogs were submitted to histologic
evaluation and to immunohistochemistry for Leishmania sp. The main lesion observed in the third
eyelid conjunctiva (TEC) was lymphoplasmacytic inflammation, with Mott cells and parasitized
histiocytes. Additionally, loss of epithelial stratification, ulceration, goblet cells thinning or hyperplasia
were often found. The same inflammatory pattern was observed in the third eyelid lacrimal gland
(TELG), often accompanied by acinar atrophy and secretory ducts dilatation. Immunohistochemistry revealed parasitism in all samples, in different intensities.
Descrição
v. 16, n. 4, p. 538-547 out./dez. 2015.
Palavras-chave
Cão, Conjuntiva, Glândula lacrimal, Leishmaniose visceral canina, Olho, Canine visceral leishmaniasis, Conjunctiva, Dog
Citação
LIMA, Aline Maria Vasconcelos; SANTOS, Adriana da Silva; FALEIRO, Mariana Batista Rodrigues; MOURA, Veridiana Maria Brianezi Dignani de; BRITO, Fábio Luiz da Cunha; BRITO, Luiz Augusto Batista. Imunomarcação de leishmania sp. e aspectos histológicos na terceira pálpebra de cães naturalmente infectados por leishmania (leishmania) chagasi. Ciência Animal Brasileira, Goiânia, v. 16, n. 4, p. 538-547 out./dez. 2015. Disponível em: < http://www.revistas.ufg.br/index.php/vet/article/view/26859/19456>.