Quantificação de β-sitosterol livre e de fitoesteróis totais no óleo de dipteryx alata vogel (BARU )
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Data
2015-09-30
Título da Revista
ISSN da Revista
Título de Volume
Editor
Flavio Marques Lopes
Resumo
The baru (Dipteryx alata Vog. Fabaceae family) is a typical plant from Brazilian cerrado whose oil extracted from the seeds is
popularly used as antirheumatic and regulator of the menstruationcycle. The interest in evaluating phytosterols in vegetable
oils is due to its application in the prevention of dyslipidemia, cardiovascular diseases and its protective activity against tumors
stimulated by estrogen.This study aimed to contribute to the chemical knowledge of the species, in particular, the relation ofthe
content of free and total phytosterols. It was necessary to develop and validate an analytical method by GC-MS to quantify free
β-sitosterol in the baru oil.The concentration of other phytosterols was estimated using their relative areas in the chromatogram.
To quantify the total phytosterols was performed a mild saponification of the oil, at room temperature in order to hydrolyze the
binding of esterification and the released phytosterols are then quantified.The total concentration of phytosterols was 1464.41
mg/kg and it was identified campesterol, stigmasterol and β-sitosterol. The concentration of free phytosterols was 1195.49
mg/kg. β-sitosterol was the major compound,found in both forms. Phytosterols identified in baru seeds allows to suggesta
correlation with the biological activity observed in its popular use.
Descrição
v.12, n. 4, p. 7-23, out./dez. 2015.
Palavras-chave
Cerrado, Cromatografia gasosa, Fitoesteróis, Estudo de validação, Gas chromatography, Phytosterols, Validation studies
Citação
MARQUES, Fernanda Garrote; OLIVEIRA NETO, Jerônimo Raimundo; CUNHA, Luiz Carlos; BARA, Maria Teresa Freitas. Quantificação de β-sitosterol livre e de fitoesteróis totais no óleo de dipteryx Alatavogel (BARU ). Revista Eletrônica de Farmácia, Goiânia, v. 12, n. 4, p. 7-23, out./dez. 2015. Disponível em: < https://www.revistas.ufg.br/index.php?journal=REF&page=article&op=view&path%5B%5D=35961&path%5B%5D=pdf>.