Hypothesis testing of genetic similarity based on RAPD data using Mantel tests and model matrices
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Data
2002-12
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Sociedade Brasileira de Genética
Resumo
Clustering and ordination procedures in multivariate analyses have been widely used to describe patterns of genetic distances. However, in some cases, such as when dealing with Jaccard coefficients based on RAPD data, these techniques may fail to represent genetic distances because of the high dimensionality of the genetic distances caused by stochastic variation in DNA fragments among the units analyzed (species or populations). In this note, we show how Mantel tests can be used to test hypotheses about genetic distances and avoid problems with multivariate data representation. The procedure is illustrated with RAPD data comparing 20 anuran species from the cerrado, in which Jaccard genetic distances were compared to three model matrices linking the species at distinct taxonomic levels.
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Anura, Clustering, Genetic distances, Mantel test, RAPD
Citação
RODRIGUES, Flávia Melo; DINIZ FILHO, José Alexandre Felizola; BATAUS, Luiz Artur Mendes; BASTOS, Rogério Pereira. Hypothesis testing of genetic similarity based on RAPD data using mantel tests and model matrices. Genetics and Molecular Biology, Ribeirão Preto, v. 25, n.4, p. 435-439, dez. 2002.