Hepatitis C virus prevalence among an immigrant community to the southern Amazon, Brazil
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Data
1999
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Resumo
A community-based random survey was conducted in a southern Brazilian Amazonian county aiming
to investigate hepatitis C virus (HCV) infection prevalence and the association of demographic variables
and lifestyle behaviours. Seven hundred eighty individuals were serologically screened with a third
generation enzyme-linked immunosorbent assay to detect anti-HCV antibodies between 1994/1995. Positive
samples were retested for confirmation with a line immunoassay (LIA, Inno-LIA HCV Ab III). Most of
these subjects were low income and came from southern Brazilian states (65.8). Two point four percent (IC
95% 1.2%- 4.6%) of the subjects had LIA-confirmed anti-HCV antibodies reactivity. The age-specific
prevalence of HCV antibodies slightly increased with age, with the highest prevalence after the age of 40
years. The results of multivariate analysis indicate a strong association between HCV antibodies and
previous surgery and history of intravenous drug use. There were no apparent association with gender,
hepatitis B virus markers, blood transfusion, and sexual activity. Mean time living in Amazon did not differ
between confirmed and negative anti-HCV individuals. The present data point out an intermediate endemicity
of HCV infection among this immigrant community to the Amazon region and that few HCV infected
participants presented known risk factors.
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Hepatitis C virus, Amazon, Emigration and immigration, Epidemiology
Citação
SOUTO, Francisco José Dutra et. al. Hepatitis c virus prevalence among an immigrant community to the southern Amazon, Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 94, n. 6, p. 719-723, 1999.