Seroprevalence of hepatitis B virus infection in individuals with clinical evidence of hepatitis in Goiás. Detection of viral DNA and determination of subtypes
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2002-12
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Resumo
The presence of serological markers for hepatitis B virus (HBsAg, anti-HBc IgM and Anti-HBc total) was investigated in the
serum of 1,396 individuals who had clinical suspect of hepatitis. It was observed that 50.7% of the individuals were positive and, from
the total of the studied individuals, 14.5% were positive for HBsAg. From these, 8.5% were also positive for anti-HBc IgM. The
analysis in relation to gender showed a higher seroprevalence index among male individuals (p < 0.0001). It was observed the
occurrence of subtypes adw 2 (62.7%), ayw 3 (23.5%), ayw 2 (9.8%) and adw 4 (3.9%). The viral DNA was detected in 61 (33.9%)
HBsAg positive samples and in one sample positive only for anti-HBc total. These results indicate an important incidence of the HBV
infection in this population, and reinforce previous studies regarding this virus in the central west region of Brazil.
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Hepatitis B, HBV-DNA, Subtypes
Citação
SILVA, Claudia de Oliveira e; AZEVEDO, Marli da Silva Pereira; Soares, Célia Maria de Almeida; MARTINS, Regina Maria Bringel; RAMOS, Carmen Helena; DAHER, Roberto Ruhman; CARDOSO, Divina das Dores de Paula. Seroprevalence of hepatitis B virus infection in individuals with clinical evidence of hepatitis in Goiás. Detection of viral DNA and determination of subtypes. Revista do Instituto de Medicina Tropical de São Paulo, São Paulo, v. 44, n. 6, p. 331-334, Nov./Dec. 2002.