Molecular characterization of group A rotavirus before and after the introduction of vaccines in Brazil
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2015-10
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Introduction: In this study, the molecular characteristics of group A rotavirus (RVA) were compared in samples obtained before
and after RVA vaccine-introduction in Brazil. Methods: Eighty samples were screened for the presence of RVA. Positive samples
were molecularly analyzed. Results: RVA positivity was 16.9%, with a predominance of G2P[4]. Periods: pre-vaccination:
predominance of IId (G1), IId (G2) lineages, and I1 and E1 genotypes; post-vaccination: predominance of Ib (G1), IIa, and
IIc (G2) lineages and I2 and E2 genotypes. Conclusions: Although changes in RVA-circulation pattern were observed in the
post-vaccination period, it could not be attributed to vaccination process.
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Rotavirus A, Gastroenteritis, Vaccine
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ALMEIDA, Tâmera Nunes Vieira; FIACCADORI, Fabíola Souza; SOUZA, Menira; BORGES, Ana Maria Tavares; CARDOSO, Divina das Dôres de Paula. Molecular characterization of group A rotavirus before and after the introduction of vaccines in Brazil. Revista da Sociedade Brasileira de Medicina Tropical, Uberaba, v. 48, n. 5, p. 599-602, Sept./Oct. 2015.