Use este identificador para citar ou linkar para este item: http://repositorio.bc.ufg.br/handle/ri/15553
Tipo do documento: Artigo
Título: Wound healing and anti-inflammatory effect in animal models of Calendula officinalis L. growing in Brazil
Autor: Parente, Leila Maria Leal
Lino Junior, Ruy de Souza
Tresvenzol, Leonice Manrique Faustino
Vinaud, Marina Clare
Paula, José Realino de
Paulo, Neusa Margarida
Abstract: Calendula officinalis is an annual herb from Mediterranean origin which is popularly used in wound healing and as an anti- inflammatory agent. In this study, the ethanolic extract, the dichloromethane, and hexanic fractions of the flowers from plants growing in Brazil were produced. The angiogenic activity of the extract and fractions was evaluated through the chorioallantoic membrane and cutaneous wounds in rat models. The healing activity of the extract was evaluated by the same cutaneous wounds model through macroscopic, morphometric, histopathologic, and immunohistochemical analysis. The antibacterial activity of the extract and fractions was also evaluated. This experimental study revealed that C. officinalis presented anti-inflammatory and antibacterial activities as well as angiogenic and fibroplastic properties acting in a positive way on the inflammatory and proliferative phases of the healing process.
País: Gra-bretanha
Unidade acadêmica: Instituto de Patologia Tropical e Saúde Pública - IPTSP (RG)
Citação: PARENTE, LeilaMaria Leal; LINO JUNIOR, Ruy de Souza; TRESVENZOL, Leonice Manrique Faustino; VINAUD, Marina Clare; PAULA, José Realino de; PAULO, NeusaMargarida. Wound healing and anti-inflammatory effect in animal models of Calendula officinalis L. growing in Brazil. Evidence-Based Complementary and Alternative Medicine, London, v. 2012, e 375671, 2012.
Tipo de acesso: Acesso Aberto
Identificador do documento: 10.1155/2012/375671
Identificador do documento: 10.1155/2012/375671
URI: http://repositorio.bc.ufg.br/handle/ri/15553
Data de publicação: 2012
Aparece nas coleções:IPTSP - Artigos publicados em periódicos

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