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http://repositorio.bc.ufg.br/handle/ri/15553
Tipo do documento: | Artigo |
Título: | Wound healing and anti-inflammatory effect in animal models of Calendula officinalis L. growing in Brazil |
Autor: | Parente, Leila Maria Leal Lino Junior, Ruy de Souza Tresvenzol, Leonice Manrique Faustino Vinaud, Marina Clare Paula, José Realino de Paulo, Neusa Margarida |
Abstract: | Calendula officinalis is an annual herb from Mediterranean origin which is popularly used in wound healing and as an anti- inflammatory agent. In this study, the ethanolic extract, the dichloromethane, and hexanic fractions of the flowers from plants growing in Brazil were produced. The angiogenic activity of the extract and fractions was evaluated through the chorioallantoic membrane and cutaneous wounds in rat models. The healing activity of the extract was evaluated by the same cutaneous wounds model through macroscopic, morphometric, histopathologic, and immunohistochemical analysis. The antibacterial activity of the extract and fractions was also evaluated. This experimental study revealed that C. officinalis presented anti-inflammatory and antibacterial activities as well as angiogenic and fibroplastic properties acting in a positive way on the inflammatory and proliferative phases of the healing process. |
País: | Gra-bretanha |
Unidade acadêmica: | Instituto de Patologia Tropical e Saúde Pública - IPTSP (RG) |
Citação: | PARENTE, LeilaMaria Leal; LINO JUNIOR, Ruy de Souza; TRESVENZOL, Leonice Manrique Faustino; VINAUD, Marina Clare; PAULA, José Realino de; PAULO, NeusaMargarida. Wound healing and anti-inflammatory effect in animal models of Calendula officinalis L. growing in Brazil. Evidence-Based Complementary and Alternative Medicine, London, v. 2012, e 375671, 2012. |
Tipo de acesso: | Acesso Aberto |
Identificador do documento: | 10.1155/2012/375671 |
Identificador do documento: | 10.1155/2012/375671 |
URI: | http://repositorio.bc.ufg.br/handle/ri/15553 |
Data de publicação: | 2012 |
Aparece nas coleções: | IPTSP - Artigos publicados em periódicos |
Arquivos associados a este item:
Arquivo | Descrição | Tamanho | Formato | |
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Artigo - Leila Maria Leal Parente - 2012.pdf | 4,64 MB | Adobe PDF | ![]() Baixar/Abrir |
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