Subcutaneoous phaeohyphomycosis by Exophiala jeanselmei in a cardiac transplant recipient

Silva, Maria do Rosário Rodrigues; Fernandes, Orionalda de Fátima Lisboa; Costa, Carolina Rodrigues; Chaul, Aiçar; Morgado, Luciano Ferreira; Fleury Junior, Luiz Fernando Froes; Costa, Maurício Barcelos

Subcutaneoous phaeohyphomycosis by Exophiala jeanselmei in a cardiac transplant recipient

Data

2005

Autores

Silva, Maria do Rosário Rodrigues

Fernandes, Orionalda de Fátima Lisboa

Costa, Carolina Rodrigues

Chaul, Aiçar

Morgado, Luciano Ferreira

Fleury Junior, Luiz Fernando Froes

Costa, Maurício Barcelos

Resumo

We report a case of phaeohyphomycosis caused by Exophiala jeanselmei in a cardiac transplant recipient maintained on immunosuppressive therapy with mycophenolate mofetil tacrolimus and prednisone. The lesion began after trauma on the right leg that evolved to multiple lesions with nodules and ulcers. Diagnosis was performed by histological examination and culture of pus from skin lesions. Treatment consisted of itraconazole (200 mg/day) for three months with no improvement and subsequently with amphotericin B (0.5 mg/Kg per day to a total of 3.8 g intravenously). After four months of treatment, the lesions showed marked improvement with reduction in the swelling and healing of sinuses and residual scaring.

Palavras-chave

Exophiala jeanselmei, Subcutaneous infections, Phaeohyphomycosis

Citação

SILVA, Maria do Rosário R.; FERNANDES, Orionalda de F. L.; COSTA, Carolina R.; CHAUL, Aiçar; MORGADO, Luciano F.; FLEURY-JUNIOR, Luiz Fernando; COSTA, Mauricio B. Subcutaneoous phaeohyphomycosis by Exophiala jeanselmei in a cardiac transplant recipient. Revista do Instituto de Medicina Tropical de São Paulo, São Paulo, v. 47, n. 1, 2005.