Subcutaneoous phaeohyphomycosis by Exophiala jeanselmei in a cardiac transplant recipient

Resumo

We report a case of phaeohyphomycosis caused by Exophiala jeanselmei in a cardiac transplant recipient maintained on immunosuppressive therapy with mycophenolate mofetil tacrolimus and prednisone. The lesion began after trauma on the right leg that evolved to multiple lesions with nodules and ulcers. Diagnosis was performed by histological examination and culture of pus from skin lesions. Treatment consisted of itraconazole (200 mg/day) for three months with no improvement and subsequently with amphotericin B (0.5 mg/Kg per day to a total of 3.8 g intravenously). After four months of treatment, the lesions showed marked improvement with reduction in the swelling and healing of sinuses and residual scaring.

Descrição

Palavras-chave

Exophiala jeanselmei, Subcutaneous infections, Phaeohyphomycosis

Citação

SILVA, Maria do Rosário R.; FERNANDES, Orionalda de F. L.; COSTA, Carolina R.; CHAUL, Aiçar; MORGADO, Luciano F.; FLEURY-JUNIOR, Luiz Fernando; COSTA, Mauricio B. Subcutaneoous phaeohyphomycosis by Exophiala jeanselmei in a cardiac transplant recipient. Revista do Instituto de Medicina Tropical de São Paulo, São Paulo, v. 47, n. 1, 2005.