Atividade antifúngica de Caryocar brasiliensis (Caryocaraceae) sobre Cryptococcus neoformans
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Data
2002-12
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Resumo
The widespread occurrence of cryptococcosis mainly in immunocompromised patients and the side
effects of available drugs which are effective against this mycosis have led investigators to search for new
antimycotic agents. Caryocar brasiliensis derived compounds were investigated against Cryptococcus
neoformans using the agar dilution method. Based on MIC values, the best results were obtained with a
concentration of ≤ 250 μ g/mL of cuticular waxes of the Caryocar brasiliensis leaf collected during the dry period
(170.8mm of precipitation) which inhibited the growth of 91.3% (21/23) Cryptococcus neoformans isolates.
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Caryocar brasiliensis, Suscetibilidade in vitro, Planta do cerrado, Cryptococcus neoformans, Caryocar brasiliensis, Antifungal activity, Cerrado plant, Cryptococcus neoformans
Citação
PASSOS, Xisto Sena; SANTOS, Suzana da Costa; FERRI, Pedro Henrique; FERNANDES, Orionalda de Fátima Lisboa; PAULA, Thaliana de Freitas; GARCIA, Ana Cristina Ferreira; SILVA, Maria do Rosário Rodrigues. Atividade antifúngica de Caryocar brasiliensis (caryocaraceae) sobre Cryptococcus neoformans. Revista da Sociedade Brasileira de Medicina Tropical, Uberaba, v. 35, n. 6, p. 623-627, nov./dez. 2002.