Cryptococcus neoformans isolados de pacientes com AIDS
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Data
2000-02
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Resumo
Cryptococcosis is considered the most frequent fungal systemic opportunist infection
in patients with AIDS. C. neoformans var. neoformans infects the patients with AIDS more often
than C. neoformans var. gattii which has been rarely isolated from patients with AIDS. Even in
endemic regions of C. neoformans var. gattii, the variety of neoformans is still the most common
agent diagnosed in cryptococcosis of patients with AIDS. Cerebrospinal fluid (CSF) from fifty
patients with neurocryptococcosis associated with AIDS were studied. The fungi were isolated in
agar Sabouraud medium, and were identified by microscopic and macroscopic examination by
agar Sabouraud, agar niger and Christensen’s urea medium. The variety was determined based
on a color characteristic reaction on glycine-L-canavanina-bromothymol blue agar. From all of
the fifty patients’ cerebrospinal fluid (CSF) we were able to recover C. neoformans. The isolates
were identified as C. neoformans var. neoformans in 47 patients and as C. neoformans var. gattii.
in the 3 remaining patients. These findings suggest that both varieties, gattii and neoformans, are
agents of neurocryptococcosis in patients with AIDS.
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Criptococose, Cryptococcus neoformans, AIDS, Cryptococosis
Citação
FERNANDES, Orionalda de F. L.; COSTA, Théo R.; COSTA, Márcio R.; SOARES, Ailton J.; PEREIRA, Ana J. S. C.; SILVA, Maria do Rosário R. Cryptococcus neoformans isolados de pacientes com AIDS. Revista da Sociedade Brasileira de Medicina Tropical, Uberaba, v. 33, n. 1, p. 75-78, jan./fev. 2000.