Resposta inflamatória e deposição de colágeno após implante intramuscular com polimetilmetacrilato em camundongos Balb/c
Carregando...
Data
2008
Título da Revista
ISSN da Revista
Título de Volume
Editor
Resumo
The tissues felling with particles has been widely used, however it is necessary to study possible adverse reactions of
these application. This study evaluated the inflammation response of collagen after intramuscular implant of
polymethilmethacrylate (PMMA) in Balb/c mice. It was implanted 100 ìl of PMMA in left hind, later the muscles were weighed
with and without implants and tissue was colleted for histopathological and immunohistochemical analysis. In the morphom-
etry found microspheres of 10.9 and 15 μm. There was a difference in the weight of the muscles p<0,01. The macrophages
phagocyting PMMA were found and there was a deposit of collagen in the conjuntive tissue. In the immunohistochemical
analysis the cells presented positive marking for CD68. The microspheres of PMMA did not lead to a chronic inflammatory
response.
Descrição
Palavras-chave
Fagocitose, Polimetilmetacrilato, Inflamação, Polimetilmetacrilato, Inflamation, Polymethilmethacrylate, Phagocitose
Citação
SOUSA, Eduardo Martins; COSTA, Eduardo Luiz; SILVA, Ediane Batista; ARAÚJO FILHO, João Alves; LINO-JUNIOR, Ruy Souza; JUNQUEIRA-KIPNIS, Ana Paula. Resposta inflamatória e deposição de colágeno após implante intramuscular com polimetilmetacrilato em camundongos Balb/c. Acta Scientiae Veterinariae, Porto Alegre, v. 36, n. 1, p. 13-19, 2008.