Angiogenic activity of Synadenium umbellatum Pax latex
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Data
2010
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Resumo
Synadenium umbellatum Pax, popularly known as “cola-nota”, is a medicinal plant that grows in tropical regions.
Latex of this plant is used to treat various diseases such as diabetes mellitus, Hansen ́s disease, tripanosomiases,
leukemia and several malignant tumors. In the present study, the angiogenic activity of S. umbellatum latex was
evaluated using the chick embryo chorioallantoic membrane (CAM) assay. Results showed significant increase of
the vascular net (p < 0.05) compared to the negative control (H 2 O). The histological analysis was in accordance with
the results obtained. In conclusion, our data indicate that S. umbellatum latex, under the conditions of this research,
presented angiogenic effect.
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Palavras-chave
Angiogenesis, Synadenium umbellatum, Latex, Chick chorioallantoic membrane, Angiogênese, Synadenium umbellatum, Látex, Membrana corio-alantóide de galinha
Citação
MELO-REIS, P. R. et al. Angiogenic activity of Synadenium umbellatum Pax latex. Brazilian Journal of Biology, São Carlos, v. 70, n. 1, p. 189-194, Feb. 2010.