Alien hand syndrome in AIDS: neuropsychological features and physiopathological considerations based on a case report

Resumo

Alien hand syndrome consists of an autonomous motor activity perceived as an involuntary yet purposeful movement, with a feeling of foreignness of the involved limb, commonly associated with a failure to recognize ownership of the limb in the absence of visual cues. A 41 year old left-handed woman, HIV positive, evolved with loss of control in the left hand. Her left hand presented extravolitional movements, as if having a will of its own, not responding to commands such as opening a door or holding an umbrella, but instead groping un-needed objects. She had talked to her hand and even fought it. In addition, other clinical presentations including recent memory loss, hemineglect and dysphoria were observed. Computed tomography revealed a hypodensity area in the right frontal-parietal region, with midline deviation. Considering clinical and epidemiological data, the diagnosis of Central Nervous System (CNS) toxoplasmosis was reached. No previous reports showing as-sociation among AIDS, toxoplasmosis and alien hand syndrome were found.

Descrição

Palavras-chave

Corpus callosum, Alien hand syndrome, Pathophysiology, Toxoplasmosis, AIDS, Frontal, Parietal, Corpo caloso, Síndrome da mão alienígena, Neuropsicologia, Fisiopatologia, Neurotoxoplasmose

Citação

CAIXETA, Leonardo; MACIEL, Patrícia; NUNES, Juliana; NAZARENO, Larissa; ARAÚJO, Letícia; BORGES, Jules Rimet. Alien hand syndrome in AIDS: neuropsychological features and hysiopathological considerations based on a case report. Dementia & Neuropsychologia, São Paulo, v. 1, n. 4, p. 418-421, 2007.