Caracterização de um isolado de trypanosoma cruzi obtido de um paciente chagásico com comprometimento cardíaco e digestivo
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Data
2009-09
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Editor
Ricardo Menegatti
Resumo
The Chagas disease is considered now neglectful and without therapeutics with
efficiency completes what has been motivating the basic research. In this work the characterization
of an isolated of Trypanosoma cruzi was aimed at obtained in a patient bearer in the heart and
digestive way of this disease in the Clinics Hospital, Federal University of Goiás. It was inoculated 40
mice to the 15 and 60 days of age with 5 x 103 or 5 x 104 trypomastigotes for animal. The
parasitemia was analyzed and other animals were sacrificed and fastened with formic aldehyde.
Fragments of the encephalon, heart, lung, tongue, esophagus, stomach, kidney, bladder, small and
thick intestine were included in paraffin, split up and red-faced with hematoxilin/eosin. Animals
submitted to the largest inoculate presented won of smaller weights and values higher parasitize. It
happened heart parasitism, focal lawsuit or diffuse, rare alterations in the other analyzed organs and
absence of deaths suggesting the classification of this isolated as stump of the type III.
Descrição
Palavras-chave
Sistema digestivo, Coração, Digestive system, Heart, Trypanosoma cruzi
Citação
SOUZA JÚNIOR, Nozelmar Borges de; OLIVEIRA, Kleber Mirallia de; SANTOS, Sara Dayane; MATA, Fabiana Ribeiro da; MATA, João Roberto da. Caracterização de um isolado de trypanosoma cruzi obtido de um paciente chagásico com comprometimento cardíaco e digestivo. Revista Eletrônica de Farmácia, Goiânia, v. 6, n. 3, p. 70-80, abr./jun. 2009. Disponível em: <https://revistas.ufg.br/REF/article/view/7652/5430>.