Ausência de mutagenicidade de solanum paniculatum l. em célula s somáticas de drosophila melanogaster: SM ART/asa
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Data
2009-12
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Editor
Vera Lúcia Gomes Klein
Resumo
The lyophilized aqueous extract of Solanum paniculatum L. (jurubeba) leaves, a medicinal plant
widely used by people as diuretic, in liver and spleen treatments, against fever and inflammation, underwent
the SMART/wing test in somatic cells of Drosophila melanogaster for the evaluation of its mutagenic potential.
We used three different concentrations of the leaf extract (2.5 mg.mL-1, 6.25 mg.mL-1, and 10 mg.mL-1),
doxorubicin (DXR) as positive control, and distilled water with 5% sucrose as negative control. We
employed three lineages of Drosophila in this experiment, flr³, ORR, and mwh. The larvae derived from
the standard cross (ST: flr³ females x mwh males) and the high bioactivation cross (HB: ORR females x
mwh males) were chronically treated and the wings of the emerging adults were analyzed. Our results
showed no mutagenic activity of S. paniculatum L. ST or HB crosses.
Descrição
Palavras-chave
Drosophila melanogaster, Genotoxicidade, Jurubeba, SMART/asa, Solanum paniculatum L, Genotoxicity, SMART/wing
Citação
RIBEIRO, Vivian; VIEIRA, Iara Lúcia Barbosa Fernandes; PASSOS, Débora Cristina Silva dos; SILVA, Elayne Miguel da; VALE, Camila Regina do; FELÍCIO, Leandro Prado; FERREIRA, Heleno Dias; VIEIRA, Pabline Marinho; CARVALHO, Salvador de. Ausência de mutagenicidade de solanum paniculatum l. em célula s somáticas de drosophila melanogaster: SM ART/asa. Revista de Biologia Neotropical, Goiânia, v. 6, n. 2, p. 27-33, jul./dez. 2009. Disponível em: <https://www.revistas.ufg.br/RBN/article/view/12851/8439>.