Equisetum arvense: scientific evidences for clinical use
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Data
2013
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Resumo
Equisetum arvense L. (horsetail) is a medicinal plant that is native to Europe and also
commonly found in the Americas, Northern Africa and Asia. It has been traditionally
indicated as a mild diuretic, antiedematous, anti-inflammatory and remineralizing treatment.
The aim of this study was to review the literature concerning horsetail to provide support to
phytotherapy researchers and policymakers interested in data on this medicinal plant. The
literature review was conducted using the PubMed, LILACS, SciELO, Virtual Health Library
(VHL), Cochrane and Scopus databases, from July 2011 to July 2012, using the uniterm
"Equisetum arvense". The study included 58 articles involving pharmacognostic,
pharmacological, pharmacokinetic, in vivo toxicological and clinical studies focusing on E.
arvense as an herbal drug or an extract. The results of preclinical pharmacological studies
demonstrate several important in vitro and in vivo biological activities, including antioxidant,
sedative, antimicrobial, antiplatelet, cytotoxic, vasorelaxant, hepatoprotective, antidiabetic,
analgesic, anti-inflammatory, wound-healing, remineralizing, antilithiasic and diuretic
activities. No clinical studies supporting the use of horsetail as a diuretic or studies on the
mechanism of action of horsetail extracts were identified. Horsetail has been classified as a traditional- and popular-use drug whose uses must be regulated and whose research needs to
be encouraged.
Descrição
Palavras-chave
Phytotherapy, Medicinal plants, Equisetum arvense, Traditional medicine, Ethnopharmacology
Citação
CARNEIRO, D. M.; TRESVENZOL, L. M. F.; JARDIM P. C. B. V.; CUNHA, L. C. Equisetum arvense: scientific evidences for clinical use. International Journal of Biology, Pharmacy and Allied Sciences, v. 2, n. 8, p. 1579-1596, Aug. 2013.