Prevalence of hepatitis A virus infection in afro-brazilian isolated communities in central Brazil
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Data
2007-02
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To investigate hepatitis A virus (HAV) infection rates among isolated African-descendant communities in
Central Brazil, 947 subjects were interviewed about demographic characteristics in all 12 isolated Afro-descendant communities existing in the state of Mato Grosso do Sul, Central Brazil, between March 2002 and
November 2003. Blood samples were collected and sera were tested for HAV antibodies (total and IgM antiHAV) by enzyme-linked immunosorbent assay. The overall prevalence of HAV infection was 75.6% (95% CI:
72.7-78.3), ranging from 55.4 to 97.3%, depending on the communities studied. The prevalence of anti-HAV
increased significantly with age, from 13.8% in the age 0-5 age group to 96.6% in those older than 40 years.
The findings point out an intermediate endemicity of HAV infection in some Afro-Brazilian isolated communities in Central Brazil. In addition, the high proportion of susceptible young subjects could be target of future
HAV vaccination programs.
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Afro-brazilian, Hepatitis A virus, Prevalence
Citação
KOZLOWSKI, Aline G.; CASTRO, Ana R. C. Motta; NASCIMENTO, Laura B.; SILVA, Ágabo M. C.; TELES, Sheila A.; VILLAR, Lívia M.; GASPAR, Ana M. C.; MARTINS, Regina M. B.Prevalence of hepatitis A virus infection in afro-brazilian isolated communities in central Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 102, n. 1, p. 121-123, Feb. 2007.