Asymptomatic coronary artery disease in chagasic patients with heart failure: prevalence and risk factors
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Data
2011
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Resumo
Background: Concomitant asymptomatic coronary artery disease in patients with Chagas cardiomyopathy in heart
failure is controversial in the medical literature, as both diseases are prevalent in some regions of Brazil.
Objetive: To determine the prevalence of coronary artery disease (lesions > 50%) in a specific population of patients
with Chagas cardiomyopathy in HF functional class III and IV, who had no previous coronary events.
Methods: Coronary angiography was performed in 61 consecutive patients with Chagasic cardiomyopathy, in heart
failure functional class III and IV, to exclude coronary artery disease. These patients were part of the Cell Therapy Study
in Heart Diseases protocol, which required the coronary angiography to be carried out before stem cells were injected.
Risk factors for atherosclerosis also analyzed in this population were: age, arterial hypertension, diabetes, dyslipidemia,
smoking and overweight.
Results: mean age was 51.6 + 9.6 years and 65.5% (n = 40) of them were males. The prevalence of coronary disease
in this population was 1.6% (1). The prevalence of risk factors were: arterial hypertension 18% (11), smoking 59% (36),
diabetes 1.6% (1) and dyslipidemia, 6.5% (4).
Conclusion: The prevalence of asymptomatic coronary artery disease in patients with severe heart failure due to
Chagas disease is low and among the risk factors for coronary heart disease, smoking was the most prevalent.
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Palavras-chave
Coronary artery disease/complications, Risk factors, Prevalence, Chagas disease, Heart failure
Citação
CARVALHO, Gustavo et al. Asymptomatic coronary artery disease in chagasic patients with heart failure: prevalence and risk factors. Arquivos Brasileiros de Cardiologia, Rio de Janeiro, v. 97, n. 5, p. 408-412, 2011.