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dc.creatorNeves, Rogério Coutinho das-
dc.creatorAndrade, Rayanny Gomes-
dc.creatorCarollo, Carlos Alexandre-
dc.creatorBoaretto, Amanda Galdi-
dc.creatorKipnis, Andre-
dc.creatorJunqueira-Kipnis, Ana Paula-
dc.date.accessioned2019-12-12T12:57:16Z-
dc.date.available2019-12-12T12:57:16Z-
dc.date.issued2019-09-
dc.identifier.citationNEVES, Rogério Coutinho das; ANDRADE, Rayanny Gomes; CAROLLO, Carlos Alexandre; BOARETTO, Amanda Galdi; KIPNIS, Andre; JUNQUEIRA-KIPNIS, Ana Paula. Hyptis brevipes and paullinia pinnata extracts and their fractions presenting activity against Mycobacterium abscessus subsp. Massiliense. Revista de Patologia Tropical, Goiânia, v. 48, n. 3, p. 148-160, jul./set. 2019. Disponível em: https://www.revistas.ufg.br/iptsp/article/view/58993.pt_BR
dc.identifier.issne- 1980-8178-
dc.identifier.urihttp://repositorio.bc.ufg.br/handle/ri/18440-
dc.description.abstractMedicinal plants are of great interest for the discovery of new biomolecules with diversified effects. Over the last decade different outbreaks caused by Mycobacterium abscessus subsp. massiliense have been reported, evidencing it as an important emerging pathogen in underdeveloped countries. This study investigated the antimycobacterial activity of six Brazilian medicinal plant extracts and their fractions. Hyptis brevipes, Tocoyena formosa, Randia armata, Paullinia pinnata, Lafoensia pacari and Anadenanthera colubrina were evaluated against M. a. massiliense. Total extracts from the medicinal plants H. brevipes, T. formosa, P. pinnata and L. pacari presented a minimal bactericidal concentration of 1 mg/ mL. After fractioning, the ethanolic fractions from H. brevipes and P. pinnata presented bactericidal activity, and the ethyl acetate fraction from H. brevipes and T. formosa presented antimycobacterial action. The best bactericidal function of all plant fractions was the ethanolic, which contained rutin and rosmarinic acid that were shown to have microbicidal activity.pt_BR
dc.description.sponsorshipUFGpt_BR
dc.language.isoengpt_BR
dc.publisherRuy de Souza Lino Juniorpt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectMycobacterium abscessuspt_BR
dc.subjectMedicinal plantspt_BR
dc.subjectBrazilian medicinal plantspt_BR
dc.subjectHPLCpt_BR
dc.subjectBiodiversitypt_BR
dc.titleHyptis brevipes and paullinia pinnata extracts and their fractions presenting activity against Mycobacterium abscessus subsp. massiliensept_BR
dc.typeArtigopt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.initialsUFGpt_BR
dc.identifier.doi10.5216/rpt.v48i3.58993-
dc.publisher.departmentInstituto de Patologia Tropical e Saúde Pública - IPTSP (RG)pt_BR
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