Does the sympathetic nervous system contribute to the pathophysiology of metabolic syndrome?

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dc.creatorMoreira, Marina Conceição dos Santos
dc.creatorPinto, Izabella Silva de Jesus
dc.creatorMourão, Aline Andrade
dc.creatorFajemiroye, James Oluwagbamigbe
dc.creatorColombari, Eduardo
dc.creatorReis, Angela Adamski da Silva
dc.creatorOliveira, André Henrique Freiria de
dc.creatorFerreira-Neto, Marcos Luiz
dc.creatorPedrino, Gustavo Rodrigues
dc.date.accessioned2021-01-08T13:28:48Z
dc.date.available2021-01-08T13:28:48Z
dc.date.issued2015
dc.description.abstractThe metabolic syndrome (MS), formally known as syndrome X, is a clustering of several risk factors such as obesity, hypertension, insulin resistance, and dislypidemia which could lead to the development of diabetes and cardiovascular diseases (CVD). The frequent changes in the definition and diagnostic criteria of MS are indications of the controversy and the challenges surrounding the understanding of this syndrome among researchers. Obesity and insulin resistance are leading risk factors of MS. Moreover, obesity and hypertension are closely associated to the increase and aggravation of oxidative stress. The recommended treatment of MS frequently involves change of lifestyles to prevent weight gain. MS is not only an important screening tool for the identification of individuals at high risk of CVD and diabetes but also an indicator of suitable treatment. As sympathetic disturbances and oxidative stress are often associated with obesity and hypertension, the present review summarizes the role of sympathetic nervous system and oxidative stress in the MS.pt_BR
dc.identifier.citationMOREIRA, Marina Conceição dos Santos et al. Does the sympathetic nervous system contribute to the pathophysiology of metabolic syndrome? Frontiers in Physiology, Lausanne, v. 6, p. e234, 2015.pt_BR
dc.identifier.doi10.3389/fphys.2015.00234
dc.identifier.urihttp://repositorio.bc.ufg.br/handle/ri/19288
dc.language.isoengpt_BR
dc.publisher.countrySuicapt_BR
dc.publisher.departmentInstituto de Ciências Biológicas - ICB (RG)pt_BR
dc.rightsAcesso Abertopt_BR
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectObesitypt_BR
dc.subjectCentral nervous systempt_BR
dc.subjectInsulin resistancept_BR
dc.subjectHypertensionpt_BR
dc.subjectCardiovascular diseasespt_BR
dc.titleDoes the sympathetic nervous system contribute to the pathophysiology of metabolic syndrome?pt_BR
dc.typeArtigopt_BR

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