Chlamydia trachomatis co-infection in HPV positive women brings no additional risk of high-grade cervical intraepithelial neoplasia

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dc.creatorCastro Sobrinho, Juçara Maria de
dc.creatorSantos, Silvia Helena Rabelo
dc.creatorAlves, Rosane Ribeiro Figueiredo
dc.creatorDerchain, Sophie
dc.creatorSarian, Luis Otávio Zanatta
dc.creatorPitta, Denise Rocha
dc.creatorCampos, Elisabete Aparecida
dc.creatorZeferino, Luiz Carlos
dc.date.accessioned2020-09-11T12:17:44Z
dc.date.available2020-09-11T12:17:44Z
dc.date.issued2015-11-20
dc.description.abstractBackground: Co-infection by Chlamydia trachomatis (CT) in women with Human Papillomavirus (HPV) infection has been shown to increase the risk of developing cervical intraepithelial neoplasia (CIN). The present study was designed to analyze the association between HPV e CT co-infection and the severity of cervical neoplasia. Methods: Two hundred fifty-one women with PCR-confirmed HPV infection were tested for CT co-infection by PCR, prior to cervical conizations due to CIN. Prevalence rates of CT and HPV types were reported for the histological diagnosis categories. Results: The prevalence of Chlamydia trachomatis was 15.1% (38/251). CT negative women showed a significant association between age ≥ 30 years and CIN 2 or worse diagnosis; this association was not found in CT positive women. In women < 29 years of age, negative for CT, the infection by HPV 16 /18 were detected in 50% of the women with CIN 2 or worse diagnosis and in 19.5% of women with CIN 1 or negative (OR=5.83; 95%CI: 2.19-15.57). Conclusion: No association with CIN 2 or worse diagnosis was observed for Chlamydia trachomatis positive women for all age groups. These data can suggest that HPV type and no CT infection may correlate with risk for severity of histological diagnoses in younger women.pt_BR
dc.identifier.citationCASTRO SOBRINHO, Juçara Maria de et al. Chlamydia trachomatis co-infection in HPV positive women brings no additional risk of high-grade cervical intraepithelial neoplasia. Journal of Cytology and Histology, Brussels, v. 2, nesp, p. 2-5, Nov. 2015.pt_BR
dc.identifier.doi10.4172/2157-7099.S3-023
dc.identifier.issn2157-7099
dc.identifier.urihttp://repositorio.bc.ufg.br/handle/ri/19032
dc.language.isoengpt_BR
dc.publisher.countryBelgicapt_BR
dc.publisher.departmentInstituto de Patologia Tropical e Saúde Pública - IPTSP (RG)pt_BR
dc.rightsAcesso Abertopt_BR
dc.rights.uriAn error occurred getting the license - uri.*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/us/*
dc.subjectHPVpt_BR
dc.subjectChlamydia trachomatispt_BR
dc.subjectPCRpt_BR
dc.subjectUterine cervicalpt_BR
dc.subjectNeoplasmspt_BR
dc.titleChlamydia trachomatis co-infection in HPV positive women brings no additional risk of high-grade cervical intraepithelial neoplasiapt_BR
dc.typeArtigopt_BR

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