Prevalence of hepatitis A virus infection in Goiânia, Goiás, Brazil, by molecular and serological procedures, 1995-2002

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dc.creatorFiaccadori, Fabíola Souza
dc.creatorSoares, Célia Maria de Almeida
dc.creatorBorges, Ana Maria Tavares
dc.creatorCardoso, Divina das Dôres de Paula
dc.date.accessioned2018-07-06T13:18:16Z
dc.date.available2018-07-06T13:18:16Z
dc.date.issued2006-06
dc.description.abstractIn this study, a total of 865 serum samples were collected between 1995 and 2002 from individuals living in Goiânia, Central Brazil, and clinically suspected of hepatitis. After exclusion of 162 samples which were positive for hepatitis B virus or hepatitis C virus, 703 samples were tested for anti-hepatitis A virus (anti-HAV) IgM antibodies by enzyme immunoassay. In addition, 588 of these samples and 22 fecal samples were analyzed by reverse transcrip- tion-nested PCR for HAV RNA detection, with positivity indices of 13.1% (77/588) and 54.5% (12/22), respectively. A similar index of viral RNA detection in anti-HAV-IgM positive or negative samples was observed in serum samples. HAV infection is a public health problem worldwide and this study underscores the extent of HAV circulation in our region.pt_BR
dc.identifier.citationFIACCADORI, Fabíola Souza; SOARES, Célia Maria de Almeida; BORGES, Ana Maria Tavares CARDOSO, Divina das Dores de Paula. Prevalence of hepatitis A virus infection in Goiânia, Goiás, Brazil, by molecular and serological procedures, 1995-2002. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, Brasil, v. 101, n. 4, p. 423-426, June 2006.pt_BR
dc.identifier.doi10.1590/S0074-02762006000400013
dc.identifier.issn0074-0276
dc.identifier.issne- 1678-8060
dc.identifier.urihttp://repositorio.bc.ufg.br/handle/ri/15355
dc.language.isoengpt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentInstituto de Ciências Biológicas - ICB (RG)pt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectHepatitis A viruspt_BR
dc.subjectGoiâniapt_BR
dc.subjectPrevalencept_BR
dc.subjectAnti-HAV-IgMpt_BR
dc.subjectViral RNApt_BR
dc.subjectBrazilpt_BR
dc.titlePrevalence of hepatitis A virus infection in Goiânia, Goiás, Brazil, by molecular and serological procedures, 1995-2002pt_BR
dc.typeArtigopt_BR

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