GB virus C/Hepatitis G virus infection in dialysis patients and kidney transplant recipients in central Brazil

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dc.creatorRamos Filho, Ramon
dc.creatorCarneiro, Megmar Aparecida dos Santos
dc.creatorTeles, Sheila Araújo
dc.creatorMatos, Márcia Alves Dias de
dc.creatorCardoso, Divina das Dôres de Paula
dc.creatorLampe, Elisabeth
dc.creatorYoshida, Clara Fumiko Tachibana
dc.creatorMartins, Regina Maria Bringel
dc.date.accessioned2019-01-15T14:48:11Z
dc.date.available2019-01-15T14:48:11Z
dc.date.issued2004-10
dc.description.abstractIn order to investigate the prevalence of GB virus C (GBV-C)/hepatitis G virus (HGV) infection in dialysis patients and kidney transplant recipients in Central Brazil and also to analyze the virus genotypes distribution, a total of 123 patients including 98 on hemodialysis, 13 on continuous ambulatory peritoneal dialysis treatment, and 12 who received kidney transplantation were interviewed in one unit of dialysis treatment in Goiânia city. Blood samples were collected and serum samples tested for GBV-C/HGV RNA by polymerase chain reaction. Genotypes were determined by restriction fragment length polymorphism (RFLP) analysis. Eighteen samples were GBV-C/HGV RNA-positive, resulting in an overall prevalence of 14.6% (95% CI: 9.2-21.7). A high positivity for GBV-C/HGV RNA was observed in patients who had received kidney transplant (16.7%), followed by those on hemodialysis (15.3%), and peritoneal dialysis (7.7%). RFLP analysis revealed the presence of genotypes 1, 2, and 3 of GBV-C/HGV; more precisely, 9 (50%) samples were found belonging to the 2b subtype, 4 (22%) to the 2a subtype, 3 (17%) to genotype 1, and 2 (11%) to genotype 3. The present data indicate an intermediate prevalence of GBV-C/HGV infection among dialysis patients and kidney transplant recipients in Central Brazil. Genotype 2 (subtype 2b) seems to be the most prevalent GBV-C/HGV genotype in our region.pt_BR
dc.identifier.citationRAMOS FILHO, Ramon et al. GB virus C/Hepatitis G virus infection in dialysis patients and kidney transplant recipients in central Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 99, n. 6, p. 639-643, 2004.pt_BR
dc.identifier.doi10.1590/S0074-02762004000600019
dc.identifier.issn0074-0276
dc.identifier.issne- 1678-8060
dc.identifier.urihttp://repositorio.bc.ufg.br/handle/ri/16731
dc.language.isoengpt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentInstituto de Patologia Tropical e Saúde Pública - IPTSP (RG)pt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectCentral Brazilpt_BR
dc.subjectHepatitis G viruspt_BR
dc.subjectGB virus Cpt_BR
dc.subjectDialysispt_BR
dc.subjectKidney transplantpt_BR
dc.titleGB virus C/Hepatitis G virus infection in dialysis patients and kidney transplant recipients in central Brazilpt_BR
dc.typeArtigopt_BR

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