Avaliação da citotoxicidade dos extratos da corrosão de mini-implantes ortodônticos de TI- 6AL-4V após imersão em saliva artificial fluoretada por 30, 90 ou 180 dias
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Data
2008-02-25
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Universidade Federal de Goiás
Resumo
The alloys used in the orthodontic therapy are subject to the corrosion process in the oral
environment. Orthodontic mini-implants Ti-6Al-4V are an excellent source for intraoral
anchorage; however, their corrosion resistance in the presence of fluoride is currently
unknown. The purpose of this in vitro study was to evaluate the cytotoxic effects of the
corrosion extracts of mini-implants Ti-6Al-4V from three different manufacturers when
exposed to 200 g/L of sodium fluoride containing artificial saliva for 30, 90 or 180 days. The
cytotoxic effects of their corrosion products on L929 cell culture was evaluated by MTT (3-
[4,5-dimethylthiazol-2-yl]2,5-diphenyltetrazolium bromide) assay, for cell metabolism and
proliferation. The extracts were not cytotoxic and the cytotoxicity assay demonstrated a
similar behavior for the samples immersed in artificial saliva in the three evaluated periods.
The qualitative analysis, through SEM did not show characteristics of corrosion. The results
indicated that the mini-implants tested presented a high corrosion resistance and
biocompatibility.
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LEMES, S. S. S. Avaliação da citotoxicidade dos extratos da corrosão de mini-implantes ortodônticos de TI- 6AL-4V após imersão em saliva artificial fluoretada por 30, 90 ou 180 dias. 2008. 65 f. Dissertação (Mestrado em Odontologia) - Universidade Federal de Goiás, Goiânia, 2008.