MIDAZOLAM ORAL NA SEDAÇÃO MODERADA DE CRIANÇAS DE UM A TRÊS ANOS DURANTE O TRATAMENTO ODONTOLÓGICO

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2009-05-15

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Universidade Federal de Goiás

Resumo

Little is known about the sedatives effectiveness for dental treatment in children under 3 years. The efficacy of oral midazolam sedation associated with protective stabilization was evaluated. In this randomized clinical trial, healthy children younger than 36 months were randomly allocated in groups: 1- protective stabilization; 2-protective stabilization associated with midazolam 1.0 mg/kg. The treatment was performed by an operator in a total of 55 sessions. A total of 26 children, 15 boys and 11 girls, were analysed: Group 1 (n = 12) - age (mean ± standard deviation) 27.50 ± 6.87, Group 2 (n = 14) - age (mean ± standard deviation) 26.86 ± 5.32. Child´s behavior was assessed using the Ohio State University Behavior Rating Scale (OSUBRS) and the heart rate record. A trained dentist recorded both behavior and physiological parameters. No difference in behaviors was found between groups on child initial examination carried out without sedation. In treatment sessions, only group 2 showed negative correlation between performance and the number of invasive Abstract procedures (Spearman rho = 0.469, P = 0.049). No significant differences between groups 1 and 2 OSUBRS scores were found in treatment sessions. The boys (77.50 ± 16.69) in group 2 showed higher percentage of negative scores (OSUBRS) than girls (26.67 ± 27.33). Statistically significant differences (Mann Whitney U test) between groups 1 and 2 were observed in heart rate during the forceps or low / high rotation use (1 = 139.67 ± 29.37 beats per minute, 2 = 164.97 ± 25.84; P = 0.003) and when the suture or rubber dam was placed (1=142,94 ± 23,19; 2=164,18 ± 23,69; P=0.005). A global analysis of children behavior during dental care was made overlooking the intervention groups (Friedman test). No associations were observed between the percentage of negative scores (OSUBRS) and several treatment sessions sequences. The percentage of negative scores (OSUBRS) was correlated with child's age (Spearman s rho =- 0.522, P = 0.006) and the percentage of negative scores in treatment the sessions (Spearman s rho = 0.405, P = 0.040). It was concluded that oral midazolam was not effective for sedation in up to 3 years old children for dental treatment purposes, and that this group of children did not change their negative behavior in the next sessions required for finishing the dental treatment planned

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FRANÇA, Cristiana Marinho de Jesus. ORAL MIDAZOLAM ASSOCIATED WITH PROTECTIVE STABILIZATION FOR DENTAL TREATMENT OF ONE TO THREE YEAR OLD CHILDREN. 2009. 90 f. Tese (Doutorado em Ciencias da Saude) - Universidade Federal de Goiás, Goiânia, 2009.