Diabetes Mellitus tipo 1: controle glicêmico e fatores de risco cardiovasculares em adultos
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Data
2012-06-29
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Universidade Federal de Goiás
Resumo
Objective: To evaluate the nutritional status, the glycemic control and the prevalence
of cardiovascular risk factors in patients with type 1 diabetes mellitus (T1DM),
attended at the nutrition and endocrinology outpatient clinic of the Goiânia Geral
Hospital (GGH). Methodology: a cross-sectional study conducted from March to
August/2011, with the following inclusion criteria: consolidated diagnosis of the
disease for at least six months, age ranging from 19 to 60 years. Fifty-two patients
were selected and interviewed, and 44 came to the clinic for collection of biological
material. Personal, socioeconomic and biochemical data were collected. Fasting
glucose (FG), glycated hemoglobin (HbA1c), lipid profile and microalbuminuria (MA)
were determined. MA and HbA1c were determined by immunoturbidimetry and FG
and lipid profile by the enzymatic colorimetric method using a Labmax Plenno
apparatus. After collecting the material, physical assessment was performed by three
trained interviewers who collected measurements of weight, height, waist
circumference and blood pressure measurement, following recommendations from
the literature. The following risk factors were evaluated: hypertension, dyslipidemia,
general obesity (BMI- body mass index), abdominal obesity (WC- waist
circumference), glycated hemoglobin, microalbuminuria, family history of type 2
diabetes, and smoking. The cutoffs recommended by the American Diabetes
Association (ADA) were adopted. Statistical analysis was performed using the
Statistical Package for the Social Sciences SPSS 18.0. Results: The average age
of patients was 30.6 ± 7.4 years, the time of diagnosis was 9.9 ± 7.1 years and
median education was 12 years. The HbA1c was inadequate in 90.9% of the
patients and 38.6% of the patients were found to be overweight (n=17). Most cases
of inadequacy of BMI, WC and total cholesterol (TC) involved females. The
prevalence of hypertension was 38.6% (n=17) and the prevalence of dyslipidemia
was 63.6% (n=28). The prevalence of inappropriate LDL, HDL, cholesterol and
triglyceride levels was 39.5%, 25%, 22.7%, and 22.7%, respectively. The prevalence
of MA was 72%. Conclusion: most patients presented unsatisfactory glucose
control. The prevalence of overweight and hypertension, of altered lipid profile, and
microalbuminuria was high.
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Citação
GONÇALVES, Alessandra Rocha. Type 1 Diabetes Mellitus: glycemic control and cardiovascular risk factors in adults. 2012. 95 f. Dissertação (Mestrado em Ciencias da Saude) - Universidade Federal de Goiás, Goiânia, 2012.