2014-09-092013-02-28CARDOSO, Natasha Queiroz. Desenvolvimento tecnológico de extratos vegetais padronizados a partir da Lafoensia pacari A. St.-Hill (Lythraceae). 2013.94 f. Dissertação (Mestrado em Ciências Farmacêuticas (FF) - Universidade Federal de Goiás, Goiãnia, 2013.http://repositorio.bc.ufg.br/tede/handle/tde/3042Lafoensia pacari A. St.-Hill (Lythraceae) popularly known as dedaleiro, didal, or mad-mangabeira pacari, is used by the Brazilian population as a febrifuge, tonic and healing. Studies have shown the antioxidant, anti-inflammatory, and antinoceptiva antiedematogenic extracts from the stem bark, ellagic acid being one of those responsible for the same. This study aimed to obtain dry extract standardized technology from the stem bark of L. pacari. The drug was tested for various quality control tests, according to the Brazilian Pharmacopoeia 5th edition, which ensured the characterization of plant drug and subsequently obtaining the liquid and dry extracts standardized. The extraction method was chosen slow percolation with 80% hydroalcoholic solution as a solvent and velocity of 7 drops per min .. The liquid extract standardized had a density of 0.986 g / mL solids content of 12.49% (w / w), pH 3.53 and an alcohol content of 44.80% (v / v). The content of ellagic acid found in liquid extract was 3.84% (m / m). The spray drying / atomization was performed by experimental design of univariate and then by planning a fractional 5-2 with 2 replicates. During the process the adjuvants were used maltodextrin and aerosil, demonstrating that the optimal conditions found maltodextrin provides greater protection and ellagic acid concentration in the extract.application/pdfAcesso abertoPlantas medicinaisÁcido elágicoExtrato secoExtrato padronizadoLafoensia pacariMedicinal plantsEllagic acidDry extractStandardized extractLafoensia pacariCIENCIAS DA SAUDE::FARMACIADissertação