2014-09-302013-10-09VILELA, Maria Helena Tavares. Ki-67, cd10, cd34, p53, cd117 e mastócitos no diagnóstico diferencial dos fibroadenomas celulares e na graduação dos tumores filóides. 2013. 45 f. Dissertação (Mestrado em Ciências da Saúde) - Universidade Federal de Goiás, Goiânia, 2013.http://repositorio.bc.ufg.br/tede/handle/tede/3229The proper management of breast phyllodes tumors (PTs) remains challenging, due to the difficulty of the correct preoperative diagnosis. The aim of this study was to evaluate the usefulness of the Ki-67, CD10, CD34, p53, CD117 and the number of mast cells for the differential diagnosis between benign PTs and cellular fibroadenomas (CFs), and also at the grading of PTs. 51 primary PTs and 14 FCs were examined by immunohistochemistry (IH). Through the evaluation of the expression of CD117, greater epithelial expression was found at the FCs and an increased number of mast cells in benign TFs. The stromal expression of the Ki-67, CD10, CD34 and p53 showed relevance to the grading of PTs.application/pdfAcesso AbertoTumores filóidesNeoplasias mamárias,Proto-oncogene c- kitKi-67P53CD34NeprilysinMastócitosFibroadenomaPhyllodes tumorsBreast tumorsProto-oncogene c-kitNeprilysinMast cellsFibroadenomaMEDICINA::ANATOMIA PATOLOGICA E PATOLOGIA CLINICADissertação