2018-06-292018-06-292006-12HERZOG-SOARES, Joanna D’Arc A.; ISAC , Eliana; CASTRO, Ana Maria de; BEZERRA, José Clecildo Barreto. Bioatividade de Stryphnodendron adstringens, S. polyphyllum, Caryocar brasiliensis, plantas do cerrado brasileiro, sobre Trypanosoma cruzi "in vivo". Bioscience Journal, Uberlândia, v. 22, n. 3, p. 113-118, set./dez. 2006.e- 1981-3163http://repositorio.bc.ufg.br/handle/ri/15325The present work verified the action of the crude extract of the Stryphnodendron adstringens, S. polyphyllum and of the Caryocar brasiliense barks, on the parasitemia of mice inoculated with cepa Y of Trypanosoma cruzi in the acute phase of the infection, evaluating its interference on the agudization or inhibition of the infectious process. Mice (Balb/C) had been infected by intraperitoneal route with 1x10 4 tripomastigotes forms, after 24 hours inoculated by intragastric route with daily doses of 400μg/ml extracts for ten days. The evaluation of the parasitemia was achieved in intervals of 2 days until the death of the animals. During the study, it was observed that the extracts of S. adstringens and S. polyphyllum had presented a higher trypanomicidal activity after the 6 th and 8 th days, occurring a higher growth inhibition in the 8 th day, when it was compared to the control group. The crude extract of C. brasiliense presented a trypanocidal activity with growth inhibition only in the 8 th day. The results demonstrated that the extracts of the tested plants presented a significant interference on the parasitemia growth of T. cruzi, reducing the number of parasites in the mice blood.porAcesso AbertoCaryocar brasilienseTrypanosoma cruziPlantasStryphnodendron polyphylluStryphnodendron adstringensCaryocar brasiliensePlantasTrypanosoma cruziStryphnodendron polyphylluArtigo