2025-04-302025-04-302019MONTALVA, C. et al. Characterization of Tolypocladium cylindrosporum (Hypocreales, Ophiocordycipitaceae) isolates from Brazil and their efficacy against Aedes aegypti (Diptera, Culicidae). Journal of Applied Microbiology, Oxford, v. 126, n. 1, p. 266-276, 2019. DOI: 10.1111/jam.14093. Disponível em: https://academic.oup.com/jambio/article/126/1/266/6714615?login=true. Acesso em: 28 abr. 2025.1364-5072e- 1365-2672http://repositorio.bc.ufg.br//handle/ri/27360To survey and to characterize entomopathogenic fungi as natural enemies of mosquitoes in Central Brazil. Methods and Results: Tolypocladium cylindrosporum (Hypocreales, Ophio cordycipitaceae) was isolated for the first time in South America by using Aedes aegypti (Diptera, Culicidae) as sentinel larvae in a stagnant mosquito breeding site in a secondary tropical forest. Two isolates were morphologically and molecularly identified, and their activity tested against A. aegypti eggs, larvae and adults. Conclusions: Findings emphasize the importance of T. cylindrosporum as a natural fungal antagonist of mosquitoes. Significance and Impact of the Study: Both isolates affected larvae and adults but were less effective against eggs; both have potential for development as a mycoinsecticide especially against larvae of A. aegypti the main vector of dengue, chikungunya, Zika and urban yellow fever.engAcesso Abertohttp://creativecommons.org/licenses/by-nc-nd/4.0/AedesAntagonistBiological controlEntomopathogenic fungiHypocrealesSouth AmericaTolypocladiumArtigo10.1111/jam.14093