2018-06-272018-06-272008ROMERO, Adriano Lopes et al. Atividade antiproliferativa de Sloanea garckeana K. Schum. Química Nova, São Paulo, v. 31, n. 6, p. 1359-1361, 2008.0100-4042e- 1678-7064http://repositorio.bc.ufg.br/handle/ri/15306The crude methanol extract and hexane, ethyl acetate, chloroform and methanol fractions from leaves of S. garckeana were examined in vitro for their antiproliferative activity on MCF-7, NCI-ADR, NCI-460, UACC-62, 786-0, OVCAR-03, PCO-3 and HT-29 human cancer cell lines. Among the assayed fractions, the ethyl acetate fraction showed to be cytotoxic against 786-0, UACC-62, OVCAR-03 and NCI-ADR cell lines with IC50 values of 12 μg/mL, 42 μg/mL, 53 μg/mL and 51 μg/mL, respectively. Through fractionation and isolation procedures compound (1) was obtained from the EtOAc fraction and its structure was elucidated by spectral techniques.porAcesso AbertoSloanea garkeanaElaeocarpaceaeO-methyl ellagic acid-4’-O-α-L-rhamnosideArtigo