2026-04-302026-04-302025MARQUES, Vitor Alves et al. Comparison of functional performance, kinesiophobia, muscle strength, quality of life, and fatigue between mastectomy and quadrantectomy in breast cancer survivors. Mastology, Rio de Janeiro, v. 35, e20250019, 2025. DOI: 10.29289/2594539420250019. Disponível em: https://mastology.org/journal/article/view/1232. Acesso em: 28 abr. 2026.2594-5394https://repositorio.bc.ufg.br//handle/ri/30212Introduction: Mastectomy and quadrantectomy are the two primary surgical procedures performed on breast cancer survivors. This study aimed to compare functional performance, kinesiophobia, and muscle strength between women who were subjected to mastectomy and those who underwent quadrantectomy. Methods: A total of 27 participants were included, divided into a mastectomy group (mean age 51.0, standard deviation ±7.83 years) and a quadrantectomy group (mean age 53.5±9.33 years). Functional performance was assessed using the Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire; kinesiophobia was measured with the Tampa Scale of Kinesiophobia (TSK); quality of life was evaluated using the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire – Breast Cancer module version 23 (EORTC BR-23); fatigue was analyzed with the Functional Assessment of Cancer Therapy – Breast cancer with arm subscale (FACT-B+4); and muscle strength was obtained through the bilateral isometric strength (BIS) and one-repetition maximum (1RM) tests. Data normality was verified using the Kolmogorov–Smirnov test. The unpaired t-test was applied to normally distributed variables, while the Mann–Whitney test was used for non-normally distributed variables. The significance level was set at p≤0.05. Results: No significant differences were found between groups regarding muscle strength (p=0.213), functional performance (p=0.635), or kinesiophobia (p=0.752). However, the mastectomy group reported lower scores in the breast symptoms domain of quality of life (p=0.050). Conclusion: Although no significant differences were observed in muscle strength, functional performance, or kinesiophobia, women in the mastectomy group reported worse quality of life in the breast symptoms domain.engAcesso Abertohttp://creativecommons.org/licenses/by-nc-nd/4.0/Breast cancerFunctional capacityKinesiophobiaPsychobiological profileSurgeryArtigo10.29289/2594539420250019