2025-12-302025-12-302025-12CAVALCANTI, Jonathan França da Silva et al. Aneurysmal bone cysts in gnathic bones: clinicopathological profile through a multicenter study and literature review. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, [s. l.], v. 140, n. 6, p. 728-739, 2025. DOI: 10.1016/j.oooo.2025.06.015. Disponível em: https://www.oooojournal.net/article/S2212-4403(25)01095-8/abstract. Acesso em: 11 dez. 2025.2212-4403e- 2212-4411https://www.oooojournal.net/article/S2212-4403%2825%2901095-8/abstractObjective To analyze the clinicopathological profile of aneurysmal bone cysts (ABCs) in gnathic bones in a Brazilian population through a multicenter study and literature review. Study Design A retrospective study across six Brazilian centers for oral and maxillofacial pathology collected data on sex, age, pain, location, radiographic features, and associated lesions. A literature review was performed using four databases. Results Among 55,068 biopsies of oral and maxillofacial lesions, 26 cases were diagnosed as ABCs. Most patients were females, with a mean age of 24.7 years. The mandible was the most affected site, and pain was absent in 76.9% of cases. A multilocular radiographic pattern with bone expansion was observed in 76.92% of cases. It was associated with ossifying fibroma and fibrous dysplasia in 11.54% and 3.85% of cases. The review included 35 articles and 59 cases, with 52.54% female patients, a mean age of 18.8 years, and mandibular involvement in 76.27%. Multilocularity with expansion occurred in 61.02%, and pain in 61.02%. Conclusions This multicenter study provides the first epidemiological estimate of gnathic ABCs (0.047%) and suggests a female and young adult predominance.engAcesso RestritoArtigo10.1016/j.oooo.2025.06.015