2023-09-052023-09-052018MEDINA, Rebeca P. et al. Anti-inflammatory and antiproliferative activities of Ixora brevifolia Benth. (Rubiaceae). Natural Product Research, Abingdon, v. 32, n. 11, p. 1357-1360, 2018. DOI: 10.1080/14786419.2017.1344654. Disponível em: https://www.tandfonline.com/doi/full/10.1080/14786419.2017.1344654. Acesso em: 28 ago. 2023.1478-6419e- 1478-6427https://www.tandfonline.com/doi/full/10.1080/14786419.2017.1344654The crude extract and fractions from the branches of Ixora brevifolia, a tree found in the Brazilian Cerrado, were tested for anti-inflammatory and in vitro antiproliferative effects. The crude extract and n-hexane fraction exhibited significant inhibition of ear oedema in mice, while n-hexane-precipitated and chloroform fractions strongly inhibited the myeloperoxidase activity in ear tissue. The n-hexane and n-hexane-precipitated fractions showed strong growth inhibition for glioma cell line and the hydromethanolic fraction inhibited the growth of leukaemia cell line.engAcesso RestritoIxora brevifoliaRubiaceaeAntiproliferative activityAnti-inflammatory activityArtigo10.1080/14786419.2017