IF - Instituto de Física

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http://200.137.215.59//handle/ri/841
O IF - Instituto de Física, da Universidade Federal de Goiás, oferece Graduação em: Bacharelado em Física; Licenciatura em Física; Física Médica; e, Engenharia Física.

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    Estudo de propriedades estruturais e espectroscópicas de nanotubos de carbono usando teoria do funcional da densidade
    (Universidade Federal de Goiás, 2024-02-02) Ferreira, Murilo Benedito Martins; Castro, Marcos Antônio de; Castro, Marcos Antônio de; Fonseca, Tertius Lima da; Georg, Herbert de Castro
    Nanotubes have intriguing properties and therefore have been the target of many investigations, both experimental and theoretical. This work will present a study on the structural and spectroscopic properties of carbon nanotubes. The goal is to investigate how geometric shapes, vibrational frequencies and other properties vary with the size and type of nanotube.
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    Foto-oxidação de proteínas por porfirinas hidrossolúveis
    (Universidade Federal de Goiás, 2024-01-29) Arantes, Ariane Gornates; Gonçalves, Pablo José; Gonçalves, Pablo José; Alonso, Antônio; Marquezin, Cássia Alessandra
    Photodynamic Therapy (PDT) is a growing therapy, indicated as an alternative to the treatment of microorganisms and various types of cancer. For its operation, three components are necessary: molecular oxygen, visible light and a photosensitizer (FS). Among the most used FS are porphyrins, which can be cationic or anionic depending on the peripheral charge of their structure. In systemic administration, FS travel through the bloodstream, making it possible to interact with body elements such as proteins, which can be photo-oxidized with controlled administration of light, losing their function, whether structurally or functionally, which can cause death. cell of target tissues. The present work analyzed the photo-oxidation of bovine serum albumin (BSA) by two cationic (TMPyP and ZnTMPyP) and two anionic (TPPS and ZnTPPS) water-soluble porphyrins. The effect of the presence of the metallic atom in the central ring of the porphyrin was analyzed; two types of irradiation sources (a halogen source and a laser module emitting at 532 mn); the effect of BSA on the production of singlet oxygen and, finally, the effect of adding constant photo-oxidation oxygen. Initially, a protocol was found that allowed the reproductive obtainment of photo-oxidation constants. Subsequently, it was observed that the photo-oxidation constant is greater for cationic porphyrins, due to their greater proximity to the fluorescent residue tryptophan, and increases with the presence of zinc, which, as it is a heavy atom, favors the process of intersystem crossing and production. of reactive species. It was also observed that the halogen lamp provides faster degradation than the laser, which may be associated with its greater spectral amplitude and could oxidize other albumin components. Furthermore, it was possible to conclude that BSA acts as an obstacle between FS and molecular oxygen, reducing the formation of singlet oxygen, which made it necessary to add oxygen gas to the solution to obtain a phosphorescence signal, which promotes a reduction in photo-oxidative rate. Our hypothesis is that rapid photo-oxidation at the beginning of the process can change the conformation of BSA, blocking oxygen access. The results obtained here are valuable for the study of protein photo-oxidation and can be extended to other biological structures targeted for studies on photodynamic action.
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    Uma proposta de sequência didática para promoção da alfabetização científica através de experimentos interativos
    (Universidade Federal de Goiás, 2024-02-02) Souza, Tiago Peron dos Santos; Queiroz, José Rildo de Oliveira; Queiroz, José Rildo de Oliveira; Cunha, Jefferson Adriany Ribeiro da; Genovese, Luiz Gonzaga Roversi
    This thesis emphasizes the growing importance of science and technology in the contemporary world and the need for a more holistic and integrated approach to science education. It highlights scientific literacy as an essential element in empowering students to understand and interact with a technologically evolving world, fostering skills like critical thinking, problem-solving and creativity. The literature review discusses the diverse interpretation of scientific literacy and its significance in developing critical and active citizens. The proposed didactic sequence focuses on the study of electricity and magnetism, combining theory and practice to develop a thorough understanding of these phenomena and their practical applications.