Uretroplastia experimental de substituição em cães com segmentos homólogos de artéria carótida conservada em glicerina

Resumo

With the aim of searching an alternative for urethral reconstruction, in this study we evaluate the urethroplasty made with homologous carotid artery, conserved in 98% glicerine, in ten dogs submitted to a partial urethra ressection. The animals were evaluated during 35 days (two dogs), 17 days (one dog) and from 3 to 12 days (seven dogs), according to the alterations which occurred during the postoperative period. The main complication observed was the urethrocutaneous fistula formation between the 3rd and 17th postoperative day, associated to hemorrhage in the extremeties of the grafts. Among the animals evaluated during 35 days, one had unimpaired urethra with normal void stream and other had diminished stream due to the partial obstruction of the urethra by epithelial hiperplasia. In both cases, the limits graft-reception site coudn’t be seen. Even at the fistula cases the patch seemed to be totally integrated to the reception site indicating adequate stabilization of the material. At the radiological studies no sthenosis were observed.The histology showed hemorrhage sites, metaplasia, neutrophils, macrophages, and fibroblasts. Plasmocits were present in only one case and they were not related to any hyperimmune reaction. The main conclusions are that the homologous segments of the carotid to the urethroplasty in dogs promotes a great amount of fistulas, postoperative hemorrhage and epithelial hiperplasia on the inner surface of the graft.

Descrição

Palavras-chave

Uretra, Uretroplastia, Carótida homóloga, Glicerina, Cão, Urethra, Urethroplasty, homologous carotid, Glicerin, Dog

Citação

PAULO, Neusa Margarida; FISCHER, Peter; MATOS, Moema Pacheco Chediack; CONCEIÇÃO, Maria da; FREITAS, José de Sousa; SILVA FILHO, Wilton Adriano da; BRITO, Wânia Clélia dos Reis; AMARAL, Andréia Victor Couto do. Uretroplastia experimental de substituição em cães com segmentos homólogos de artéria carótida conservada em glicerina. Ciência Animal Brasileira, Goiânia, v. 1, n. 1, p. 65-71, jan./jun. 2000. Disponível em: <https://www.revistas.ufg.br/vet/article/view/235/199>.