Humoral immune responses of tuberculosis patients in brazil indicate recognition of Mycobacterium tuberculosis MPT-51 and GlcB
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2008-03
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The humoral responses to recombinant MPT-51 and GlcB was determined by using an enzyme-linked
immunosorbent assay. Levels of immunoglobulin M (IgM) against MPT-51 and IgG against GlcB were higher
among tuberculosis (TB) patients than among control individuals. When the MPT-51 and GlcB assays were
combined, 90.8% specificity and 75.5% sensitivity were observed. MPT-51 and GlcB were recognized in the
humoral responses of Brazilian TB patients.
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MELO, Cristina Cardoso de et. al. Humoral immune responses of tuberculosis patients in Brazil indicate recognition of Mycobacterium tuberculosis MPT-51 and GlcB. Clinical and Vaccine Immunology, Washington, v. 15, n. 3, p. 579-581, 2008.