Prevalence of hepatitis C virus infection among hemophiliacs in central Brazil
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Data
2002-07
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Resumo
In order to investigate the hepatitis C virus (HCV) infection prevalence and risk factors in hemophiliacs in
Central Brazil, 90 patients were interviewed and serum samples tested for HCV RNA and anti-HCV antibodies. An
overall prevalence of 63.3% (CI 95%: 53.0-72.7) was found. Multivariate analysis of risk factors showed that
number of blood transfusions was significantly associated with this infection. Most hemophiliacs received locally
produced cryoprecipitate. All infected patients were transfused before the screening of blood units for anti-HCV.
However, hemophiliacs who received exclusively screened cryoprecipitate were HCV negative. It confirms the
expected decline in transfusion-acquired hepatitis C.
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Palavras-chave
Hepatitis C, Hemophilia, Prevalence, Central Brazil
Citação
BARBOSA, Adriana P.; MARTINS, Regina M. B.; TELES, Sheila A.; SILVA, Simonne A.; OLIVEIRA, Jaqueline M.; YOSHIDA, Clara F. T. Prevalence of hepatitis C virus infection among hemophiliacs in central Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 97, n. 5, p. 643-644, July 2002.