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dc.creatorCastro, Ana Rita Coimbra Motta de-
dc.creatorYoshida, Clara Fumiko Tachibana-
dc.creatorLemos, Elba Regina Sampaio de-
dc.creatorOliveira, Jaqueline Mendes-
dc.creatorCunha, Rivaldo Venâncio da-
dc.creatorRodrigues, Lia Laura Lewis Ximenez de Souza-
dc.creatorAcero, Pedro Hernan Cabello-
dc.creatorLima, Kátia Mougenot Barbosa-
dc.creatorMartins, Regina Maria Bringel-
dc.identifier.citationCASTRO, Ana Rita Coimbra Motta de el al. Seroprevalence of hepatitis B virus infection among an afro-descendant community in Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 98, n.1, p. 13-17, Jan. 2003.pt_BR
dc.description.abstractFurnas dos Dionísios is an Afro-Brazilian black community whose descendants were mainly fugitive slaves that established themselves in the State of Mato Grosso do Sul (MS), Brazil. The population is comprised mainly of low socioeconomic individuals who are engaged in agricultural activities. The objective of this study was to investigate the prevalence of hepatitis B (HB) and its correlation with epidemiological data obtained from the community. The studied population totaled 260 individuals with ages varying from 1 to 79 years (median 20). One hundred thirtythree (51.2%) were females and 127 (48.8%) were males. A high prevalence for anti-HBc was observed (42.7%), with present infection detected in 9.2% of the subjects who were also HB surface antigens (HBs Ag) positive; 27.3% were anti-HBc and anti-HBs reactive, and 6.2% had anti-HBc as only marker. The prevalence for anti-HBc was proportional to age, reaching its highest peak in age categories greater than 50. No serological marker was detected in children under the age of 2 years, however anti-HBc was present in 12 subjects with ages between 2 and 14 years, of these 8 (7.4%) were HBsAg positive. Among individuals over the age of 15 years, 99 were anti-HBc reactive, of these 16 (10.5%) were also HBsAg positive, thus suggesting an increased prevalence of HBV carriers among children and adolescents. The risk factors observed in this community that were significantly associated with anti-HBc positivity were age (over 20 years) and having an anti-HBc positive mother. Both HBeAg and anti-HBe were detected in 44.4% of the samples tested. HBsAg subtypes found in the studied population were adw2 (77.7%) and ayw2 (23.3%). While intrafamilial transmission was most likely responsible for HBV infection among children, other routes such as sexual contact might be considered for individuals with ages over 15 years.pt_BR
dc.rightsAcesso Abertopt_BR
dc.rights.uriAn error occurred getting the license - uri.*
dc.rights.uriAn error occurred getting the license - uri.*
dc.subjectHepatitis Bpt_BR
dc.titleSeroprevalence of hepatitis B virus infection among an afrodescendant community in Brazilpt_BR
dc.publisher.departmentInstituto de Patologia Tropical e Saúde Pública - IPTSP (RG)pt_BR
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