Beta-caroteno e câncer
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Data
1998-12
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Resumo
The subject β-carotene and cancer has been studied for more than twenty years, through
epidemiologic and experimental researches.Observational epidemiologic studies, both
prospective and retrospective, have suggested strongly that high intake of vegetables and
fruits which are sources of β-carotene is associated with reduced risk of cancer, specially
of lung cancer. However, the results of intervention trials do not demonstrate a preventive
potential of β-carotene. Nevertheless, in many studies in experimental animals and in cell
cultures, this carotenoid had been shown to act as a potent cancer chemopreventive agent
and mechanisms have been proposed to explain this protective effect on biological systems.
Researchers suggest that β-carotene protects against cancer, in the amounts easily
attained by the consumption of a wide variety of diets, and the chronic pharmacological
supplementation is not recommended for healthy populations and for heavy smokers.
Descrição
Palavras-chave
Epidemiologia nutricional, Beta-caroteno, Carotenóides, Quimioprevenção, Neoplasias, Carcinógenos, Nutritional epidemiology, Beta-carotene, Chemoprevention, Carotenoids, Neoplasms, Experimental carcinogens
Citação
NAVES, Maria Margareth Veloso. Beta-caroteno e câncer. Revista de Nutrição, Campinas, v. 11, n. 2, p. 99-115, jul./dez. 1998.