Programa de Pós-graduação em Odontologia

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Comparação entre implantes unitários de superfície tratada e não tratada por sub-tração radiográfica digital em protocolos de carga imediata e convencional
(Universidade Federal de Goiás, 2009-03-27) CARNEIRO, Luciano Sandoval; MENDONÇA, Elismauro Francisco de; http://lattes.cnpq.br/2305019128015847
Objectives: To compare by digital subtraction radiography (SR), matched to clinical evaluation, bone response to single-tooth treated (TS) and non-treated (NTS) surface implants on immediate (IM) and conventional (CO) loading protocols. Material and methods: 12 patients (8 underwent IM protocol and 4 underwent CO protocol) received 24 implants. Each subject received 2 implants (one with TS and the other NTS) homologously and bilaterally positioned in maxillae (lateral incisor, canine or premolar regions) or mandible (molar area). Standardized radiographies of each implant were taken on the day after implant placement (baseline image) and after 3, 6 and 12 months (follow-up images). SR was used for crestal bone loss (CBL) and peri-implant bone density (PIBD) measurements. The placement torque and resonance frequency (at 0, 6 and 12 months) were also measured for matching radiographic data. Results: T-test revealed no statistically significant difference in CBL between TS and NTS implants, while TS implants presented higher PIBD in the mid-implant region at 3-months recall (p = 0.04). For IM protocol, the Mann-Whitney test revealed higher CBL at 6-months follow-up (p = 0.03), greater PIBD at 12-months recall (p = 0.06; p = 0.07) and increasing PIBD through time. There was a positive correlation between primary stability and PIBD at 12-months recall (r = 0.58; p = 0.005). Conclusions: TS and NTS implants presented similar performances with regard to CBL and PIBD. IM and CO protocols were similarly successful. Primary stability was an important element in reaching greater PIBD after 1-year loading period
Saúde bucal de crianças hospitalizadas: percepções e atitudes de acompanhantes
(Universidade Federal de Goiás, 2010-04-27) CORTINES, Andréa Araujo de Oliveira; COSTA, Luciane Ribeiro de Rezende Sucasas da; http://lattes.cnpq.br/9906371509661305
Attitudes towards oral health may contribute to the recovery of hospitalized child s general health. For the development of educational and preventive programs directed to this public, it is necessary to comprehend the perceptions about oral health according to care-givers, in order to elaborate a project of health education, giving importance to the knowledge and attitudes of this group. A qualitative research was accomplished through interviews, based on semi-structured itinerary. The interviews were recorded in audio-cassette, transcribed, typed and printed to obtain the material of the study: the interviewees speeches. The data analysis was based on the content analysis, thematic modality, accomplished through the exhausting reading of all the interviews in order to extract the meaningful words and sentences, getting them into sense nuclei and later classifying them in themes. Three themes were inferred as results: The care, The oral health and The relationship between oral health and general health. In relation to the care offered to hospitalized children, it is different from that destined to the same child before getting sick and also to the other children of the family through the increase of the devotion, of the concern with the child's comfort, in order to soften the pains and the suffering and of the feeding. The subjects reports demonstrated that the concern with the oral health happens through the accomplishment of the dental care and also through the accomplishment of the oral hygiene at least three times a day, using toothpaste and toothbrush. However it is noticed that there is not to be concern with other risk factors as the diet and the use of medicines and not even in following some orientations received by surgeon-dentists or to look for a preventive treatment. Some of the care-givers also demonstrated difficulty in accomplishing or supervising the child's oral hygiene. For some of them, the hospitalization is not a factor which makes more difficult the accomplishment of the oral hygiene, because this is a habit, while for other it is, because they leave the domestic routine. In relation to the theme "relationship oral health - general health", it is noticed that they believe in a bi-directional relationship among them, however, they think that what really interferes in the child's oral health is not the disease itself, but the fact of using antibiotic. The conclusion was that the companions' perceptions about the hospitalized children's oral health follow the common sense that the action of brush the teeth is part of the corporal hygiene and that this practice should happen three times a day, with the use of toothbrush and toothpaste, without considering other risk factors. The care-givers get to notice their children's real oral conditions and try to make them better with the healing treatment and not avoiding them through the prevention. The attitudes in relation to health are permeated by faiths as that the antibiotic, "strong medicine", destroys the teeth. Actions in health education must be developed together with the whole multiprofessional team of health and with the target group in order to promote a change in the way people see the process health-disease.
Avaliação da expressão da granzima b e sua relação com o prognóstico do carcinoma espinocelular de boca
(Universidade Federal de Goiás, 2010-02-26) COSTA, Nádia do Lago; BATISTA, Aline Carvalho; http://lattes.cnpq.br/0199082642322002
The cytotoxic T lymphocytes (CTL) and natural killer (NK) cells are more effective in fighting cancer because these cells recognize tumor cells and release cytotoxic granules rich in perforin and granzyme B (GB). The perforin form pores in tumor cells allowing the influx of GB. When inside the cell, the GB promotes tumor cell death through apoptosis. In this context, high expression of GB into the microenvironment of different types of cancers has been considered a key event for effective antitumor immunity. Therefore, the objective of this study was to identify and quantify GB+ cells, peri- and intratumoral, and its relationship with clinical prognostic parameters (size of the primary lesion, location, metastasis and survival) and microscopic (microscopic grading and cell proliferation index and apoptosis of neoplastic cells) of squamous cell carcinoma (SCC) of the oral cavity. GB+ cells were identified by the technique of immunohistochemistry, a method of polymer, in 20 samples from patients with SCC of the oral cavity that had metastasized to cervical lymph nodes and in 35 samples from patients with SCC of the oral cavity without metastasis to cervical lymph nodes. Our results showed that the density of peritumoral GB+ cells was significantly higher in the non-metastatic SCC when compared with metastatic group (p=0.03). In addition, patients with high expression of peritumoral GB had a longer survival than those with low expression of this protease (Kaplan Meier, Log Rank p=0.02). We showed also that patients with high density of peritumoral GB+ cells showed a low percentage of neoplastic cells bcl2+ (antiapoptotic protein) (P=0.004) and high density of neoplastic cells Bax+ (apoptotic protein) (p=0.031) when compared to the group of low density of peritumoral GB+ cells. In agreement with these data, patients who had a high density of peritumoral GB+ cells showed high expression of Annexin V by neoplastic cells. Additionally, the density of GB+ cells intratumoral and peritumoral was significantly higher in the T1 and T2 (39.44±7.21 and 14.61±3.60, respectively) when compared to T3 and T4 (31.03±3.76 and 11.90±1.88, respectively), however these results were not statistically significant (p>0.05). The association between the density of cells GB+ and other characteristics of SCC of the oral cavity, such as location, tumor proliferation and tumor grading was not observed. Our findings suggest that the increased of expression of GB in tumor microenvironment of SCC of the oral cavity may have beneficial effect against neoplastics cells, contributing to apoptosis of these cells, lower lymph node involvement and increased survival time of patients.
Expressão de reguladores da reabsorção óssea (RANK/RANKL/OPG) e formação óssea (osteocalcina) em lesões realcionadas ao osso e osteossarcoma
(Universidade Federal de Goiás, 2010-03-19) ELIAS, Larissa Santana Arantes; MENDONÇA, Elismauro Francisco de; http://lattes.cnpq.br/2305019128015847
The RANK (receptor activator of nuclear factor Kappa-Beta)-RANKL (receptor activator of nuclear factor-kappa beta ligand)-OPG (osteoprotegerin) system is the principal means of differentiating and activating osteoclasts. Changes along this path have been associated with various bone related lesions (BRL), whether benign or malignant, such as osteosarcoma (OS). This system induces resorption when it is deregulated, and in the case of LROs, by replacing the bone tissue for fibrous tissue with the presence of various forms of ossification. And in this same context another protein, osteocalcin (OC), a marker of late ossification, plays a key role in the diagnosis of these lesions. This being so, the objective of this study was to identify, quantify and compare cell RANK+, RANKL+, OPG+ and OC+ in lesions of the jaw with bone involvement: ossifying fibroma (OF), fibrous dysplasia (FD), simple bone cysts (SBC), central giant cell lesions (CGCL) and osteosarcoma (OS) so as to contribute to understanding the pathogenesis and establishing the diagnosis of these lesions. RANK+, RANKL+, OPG+ and OC+ cells were identified by the technique of immunohistochemistry, a method of immunoperoxidase and polymer, in 10 samples of OF, FD, SBC, CGCL and 5 samples of OS. Our results showed that all samples were positive for RANK, RANKL, OPG and OC. In the stromal fibroblast-like cells, the OF (P<0.001), CGCL (P=0.007) and OS (P=0,058) presented a greater expression of RANKL than OPG, in contrast with both the SBC (P=0.003) and the FD (P<0.001). As for bone-matrix (cells around bone/osteoid-osteoblast and osteoclast), the OS (P=0.24) and OF (P=0.001) samples demonstrated a higher RANKL immunoreactivity and and a lower in FD (P=0.001) and SBC (P=0.4) samples. In terms of OC, a higher expression was shown in FD, SBC, and OS (P=0.008). Our results suggest that OF, CGCL and OS express bone metabolism regulators, which may be related to increased bone resorption in these lesions. In addition, osteoblastic involvement was seen in FD and OS. Note: The superscript + is where it appears. Programs to copy some formatting errors.
Os Processos Formativos dos Professores dos Cursos de Graduação em Odontologia no Estado de Goiás e o Contexto de Implementação das Diretrizes Curriculares Nacionais
(Universidade Federal de Goiás, 2010-08-16) FRANCO, Lila Louise Moreira Martins; QUEIROZ, Maria Goretti; http://lattes.cnpq.br/7079676967280121; MARCELO, Vânia Cristina; http://lattes.cnpq.br/6650368201862218
The professors of the graduation courses in Dentistry are considered unprovided of certain types of knowledge which are inherent to the practice of higher education due to the fact that they are graduated in a bachelor‟s degree mode. Therefore, a question arises: how are they educated to practice teaching? For this reason, we present a short history about the interface health and higher education and this professor‟s educational processes. We also discourse upon the National Curriculum Guidelines for the graduation courses in Dentistry because those guidelines propose changes in the profile of the professionals, which demand a need for changes in the profile of the professor who educates those professionals. The present study aimed at analyzing the educational processes of the professors of the graduation courses in Dentistry and the context of implementation of the National Curriculum Guidelines. For this purpose, we investigated the pedagogical projects of the courses regarding teaching; we raised the professors‟ academic profile, the identification of experiences related by professors about their educational processes and perspectives in the context of implementation of the National Curriculum Guidelines, as well as the verification of the relation of those processes and the professors‟ knowledge of that document. We developed the study in the State of Goiás within the years of 2009 and 2010 and we used a quanti-qualitative methodology in three stages: analysis of documents, a self-applicable questionnaire, and a semi-structured interview. We opted for thematic analysis, which is one of the types of content analysis, and we made use of data triangulation. The main results we found were: there is little mention of potential educational processes in the Pedagogical Projects of the courses; the educational processes we found include family influence, schooling, interpersonal relationships, culture, socio-geographical characteristics, leisure activities, and professional experience. The professors presented little knowledge about the National Curriculum Guidelines and we did not find a direct relation between this knowledge when one or another educational process in present. The professors‟ formation does not take place in the professional dimension only. It is also personal, and the actors who are involved in this formation can be gathered as individual, collective, and/or institutional
Expressão da proteína Ki-67 e da glicoproteína MUC1 em carcinomas mucoepidermóide de glândulas salivares menores
(Universidade Federal de Goiás, 2009-05-22) GONÇALVES, Cintia Ferreira; BATISTA, Aline Carvalho; http://lattes.cnpq.br/0199082642322002; MENDONÇA, Elismauro Francisco de; http://lattes.cnpq.br/2305019128015847
Aims: Investigate the prognostic significance of cellular proliferation indexes and mucosecretional activity in Mucoepidermoid Carcinoma (MEC) of oral cavity minor salivary glands using the immunoexpression of the protein Ki-67 and the glycoprotein MUC1 in young people and adults, by correlating these markers to clinical and pathological parameters. Material and methods: From 1987 to 2007, 35 cases of MEC were diagnosed in minor salivary glands. Demographic clinical data were obtained from clinical records, the microscopic diagnosis was revisited and the specimens were reclassified in terms of histologic grading, according to the system used by Batsakis & Luna (1990). Qualitative and quantitative analyses of the expression of Ki-67 protein and MUC1 glycoprotein, obtained through immunohistochemistry, were correlated to the variables: age, gender and histologic grading. Results: The cases of MEC (n=35) were more frequently found in people over thirty (60%), with predilection for females (1.7:1) and occurred most frequently in the hard palate (54.3%). Of the cases studied, 42.9% were low grade, 37.1% intermediate and 20% high grade. A greater expression of Ki-67 was found for adults while the greater expression for young people was MUC1, although neither result was statistically significant (Ki-67 / P=0.44 e MUC1 / P=0.5). In addition no prognostic relation was seen between male and female, despite the greater expression of both markers for males (Ki-67 / P=0.58; MUC1 / P=0.4). In terms of histologic grading intermediate and high grade tumors presented a greater expression for both markers, but without any statistical significance (Ki-67 / P=0.18; MUC1 / P=0.6). Conclusions: MEC in minor salivary glands could present a tendency of lesser aggressiveness in younger patients when compared to adults; in females when compared to males, and in tumors of low histologic grade when compared to those of intermediate or high grade. Furthermore, this tumor may have a tendency to higher mucossecretory activity in young than in adults, in males than in females and in intermediate and high grade tumors.
Cárie dentária, aquisição de açúcar e fatores socioeconômicos em crianças e adolescentes brasileiros: um estudo ecológico
(Universidade Federal de Goiás, 2010-12-22) GONÇALVES, Michele Martins; FREIRE, Maria do Carmo Matias; http://lattes.cnpq.br/6056344372250078
The aim of this study was to investigate associations between dental caries experience at ages 5, 12 and 15-19 and household sugar availability in the Brazilian capitals using data from the Household Budget Survey 2003. Associations between dental caries, socioeconomic indicators and access to fluoridated water supply were also tested. The data on caries experience were obtained from the national survey of oral health in 2003 and socioeconomic indicators from the United Nations Development Programme. Correlation tests and linear regression were used in the statistical analysis. The availability of soft drinks and per capita income were negatively associated with the DMFT at age 12. At 12 and 15-19 years-old dental caries experience was also negatively associated with the HDI and fluoridated water, and positively associated with the rate of illiteracy. The results indicate the importance of socioeconomic factors and of fluoridation water in dental caries experience, which seem to influence the effect of sugar.
Avaliação de dispostivo alternativo ao arco facial para montagem de modelos em articuladores semi-ajustáveis
(Universidade Federal de Goiás, 2011-04-26) HARTMANN, Roberto; ROCHA, Sicknan Soares da; http://lattes.cnpq.br/8256226109956656
The aim of this study was to analyze the face-bow and three different camper planes, 0°, 15° e 20°, regarding the placement of maxillary cast and the fidelity of reproduction of occlusal contacts of casts mounted in semi-adjustable articulator arcon type. Were selected nine students over 18 years showing complete natural dentition whose cast maxillaries presented stable on surface plane. The 36 cast maxillaries were mounted in a single semi-adjustable articulator using four different techniques: facebow, camper plane of 0º, camper plane of 15º and camper plane of 20º. The first analysis was considering the position of the cast maxillary. On each side of the articulator were defined three points: one in the articulator, the condylar region (A) and two in the cast (B and C). Point B was positioned at the lower first molar buccal groove (intercuspal region) and C at the midpoint of the first molar (mesio-distal), 1cm above the intercuspal region. Through the digital camera (Rebel XTi) positioned at a standard distance of 1.15 m of articulating images were obtained on each side of the articulator. Using the software Image J was given angle "α" formed by the intersection of the line segments AB and BC. For analysis reproducibility of occlusal contacts the cast mandibles were mounted in maximum intercuspation. The points of contact clinical and casts were recorded with carbon Accufilm. The area (mm2) of the points of contact on the lower left first molar of each group was quantified in Image J software, using images obtained with a digital camera (Rebel XTi). As for the positioning of the cast maxillary no significant difference was found just between the plane and the face-bow (p<0.001). None of the mounting techniques were effective in reproducing clinical contact points (p<0.001).
Critérios de Diagnóstico para Pesquisa das Desordens Temporomandibulares (RDC/TMD): avaliação de radiologistas sobre adequação
(Universidade Federal de Goiás, 2011-02-28) MACHADO, Luciana Pimenta e Silva; RIBEIRO-ROTTA, Rejane Faria; http://lattes.cnpq.br/9466795079344876
The aim of this study was to investigate the opinion of specialists in radiology, from different parts of the world, regarding to the proposed criteria for image acquisition and interpretation by Computed Tomography (CT), Cone Beam Computed Tomography (CBCT) and Resonance imaging (MRI) in diagnosing temporomandibular joint disorders (DATM) as part of Diagnostic Criteria for Research of Temporomandibular Disorders (RDC/TMD). Radiology specialists were invited by email to participate as volunteers in the study from three different eligible populations: researchers with publication DATM indexed on PubMed, ORADLIST members and individual contact. The link to access the questionnaire was mailed to volunteers interested in participating who matched the inclusion criteria. The sample was composed of specialists in radiology with experience in the interpretation of sectional images (CT, CBCT and/or MRI) of the temporomandibular joint (TMJ) who answered a questionnaire in English, which was developed and maintained online (LimeSurvey 1.87+). In a three months period, two recalls were sent and a period of 40 days after the last notification was given for responses submission. The questionnaire was divided into three parts with closed and open questions. Part I was related to issues of participant identification (gender, age, country of activity, area of activity, time and experience as a radiologist in the interpretation of sectional images of the TMJ and monthly time dedicated to the activity of interpreting sectional images of ATM). Part II contained questions related to the adequacy of the proposed criteria for the interpretation of sectional images of the ATM as part of the RDC/TMD. The criteria were presented into two columns' tables and the participants were asked whether that set of criteria was considered adequate or not for assessement and diagnosis of TMJ osseous and non-osseous tissues according to each imaging modality. If the respondent not considered criteria appropriate, he/she should indicate what type of suggestion: if insertion of new items, the modification or deletion of existing items. Part III had questions related to the need to include a minimal technical protocol for TMJ CT, CBCT and MRI acquisition as part of the RDC/TMD. If deemed necessary, the respondent should indicate which would be his/her suggestion protocol for acquisition of each imaging technique (CT, CBCT and MRI). Fifty-seven radiologists from different countries completed the questionnaire. The results indicate that 87 to 98% of radiologists considered the criteria adequate and that 81.6% of respondents considered necessary to include a minimal technical protocol for CT, CBCT and MRI acquisition as part of the RDC/TMD. Two to thirteen percent of respondents suggested insertion, modification and deletion of items in the proposed criteria. Ninety percent of respondents considered necessary to include a minimal technical protocol for CT/CBCT and 81.7% for MRI. We conclude that, according to the opinion of the worldwide community of specialists in radiology, the need for adjustments in the criteria for assessment of sectional images of the ATM is minimal, however, the need for the inclusion of a protocol to acquire minimal technical parameters of those images as part of protocol standardization of studies using the RDC/TMD is clear.
EFICÁCIA DE DIAGNÓSTICO DA TOMOGRAFIA COMPUTADORIZADA E RESSONÂNCIA MAGNÉTICA NO TRATAMENTO DAS DESORDENS DA ARTICULAÇÃO TEMPOROMANDIBULAR: UMA REVISÃO SISTEMÁTICA
(Universidade Federal de Goiás, 2009-04-22) MARQUES, Karlla Dias Siqueira; RIBEIRO-ROTTA, Rejane Faria; http://lattes.cnpq.br/9466795079344876
Diagnosis of disorders affecting the temporomandibular joint (TMJ) is a difficult task for many reasons. These include the structural and functional complexity of this joint, the multifactorial origin of these disorders and limited knowledge of their natural course, the presence of common symptoms among its various subclasses and other craniofacial conditions. If the premise for effective treatment is a correct diagnosis, it is clear that the treatment of these disorders is not any less complex than their diagnosis. The aim of this study was to do a systematic analysis of the literature in relation to proof of the therapeutic efficacy of computed tomography (CT) and magnetic resonance imaging (MRI) in the treatment planning of TMJDs (disc displacement, inflammatory disorders without systemic involvement or osteoarthosis). This systematic review was comprised of three steps: (1) Specifying the problem and the inclusion/exclusion criteria used in the publications; (2) Formulation and detailing of a plan to conduct the literature search; (3) Interpretation and integration of the evidence in the studies and formulation of recommendations based on the quality of the evidence. The bibliographical search was undertaken in PubMed and Cochrane Library databases from January 1966 to July 2009, using specific indexed terms, selected according to the objectives. The titles and abstracts found were analyzed by three examiners and the publications fulfilling the inclusion criteria were selected. The same three examiners read the full texts of these selected publications, and extracted data with the help of a previously drawn up protocol. A publication was considered relevant and included in the review when its results expressed any type of impact of the information obtained with CT and MRI on the treatment of disc displacement, local inflammatory disorders or osteoarthosis therapeutic efficacy. Publications considered relevant were interpreted with the aid of the Quality Assessment of Diagnostic Accuracy Studies (QUADAS) tool and publications that critically evaluate systematic reviews. Results: The literature search yielded 584 titles and abstracts, of which 257 were selected and read in full text. One study was judged relevant. This study evaluated evidence of the efficacy of magnetic resonance imaging (MRI) in the diagnosis of disc position and configuration, disc perforation, joint effusion, and osseous and bone marrow changes in the temporomandibular joint, but no publication reported diagnostic thinking efficacy or therapeutic efficacy. The absence of studies on the therapeutic efficacy of CT and MRI on TMJD reinforces the need for investment in decision-making studies; meanwhile, sectional imaging tests should be prescribed with caution, especially when health budgets are limited.
Motivos determinantes da eleição ou recusa de tipos de tratamentos protéticos em desdentados parciais
(Universidade Federal de Goiás, 2008-03-03) MARTINS, Rafael Ragonezi; LELES, Claudio Rodrigues; http://lattes.cnpq.br/6740286066154410
The aim of the study was to explore preferences and reasons for choosing or refusing prosthetic treatments in partially edentulous patients. Clinical and oral-related quality of life measures were collected from 165 patients undergoing dental treatment in undergraduate clinical activities in the School of Dentistry of the University Federal of Goiás. Reasons for choosing or refusing prosthetic treatments were investigated using an instrument containing 32 questions about the importance of these items for the patient s decisions about treatment in a 5-point Likert scale, ranging from 1 (no importance) until 5 (absolutely important). Descriptive statistics, chi-square and ANOVA were used to compare patients preferences according to clinical independent variables. Discriminant analysis was used to analyze the impact of patients reasons for choosing or refusing removable (RPD), fixed (FD) or implant (ID) prosthesis. Results showed that older patients (p<0.001) and with greater OHIP scores (p<0,05) were more likely to choose for removable partial dentures and implant prosthesis were preferred in patients with higher school levels (p<0.01). Discriminant functions reveal that the desire of having a fixed or removable appliance had great impact on patients decisions. The removal of natural teeth structure was the main reason for refusing conventional fixed dentures and cost had great impact on refusing implant dentures. Overall agreement percentages between actual patients decisions and predicted by discriminate analysis were over 90% for all types of treatment. It was concluded that acceptance or rejection of prosthodontic modalities have great variations among patients and individual perceptions are important determinants of treatment decisions. The main reasons for choosing or refusing treatments focused in this study can be used to guide shared decision making process, providing treatments that better match patients expectations and desires
Avaliação de erros operatórios durante o preparo do canal radicular após o uso de instrumentos rotatórios de níquel-titânio realizados por estudantes e especialistas
(Universidade Federal de Goiás, 2010-02-26) OLIVEIRA, Henrique Cesar Marcal de; ESTRELA, Carlos; http://lattes.cnpq.br/3611967334176683
The aim of this study was to determine the errors of procedures that occurred during the preparation of curved root canals after the use of instruments níqueltitânio powered motor managed by specialists in endodontics and dental students. Forty upper and lower molars of humans were randomly divided into two groups of 20, according to traders: G1A-(Molars, specialists in endodontics), G1B-(lower molars, specialists in endodontics), G2A-(molars, dental students), G2B-(lower molars, dental students). The ProTaper Universal System was used to prepare all root canals. The AH PlusTM associated with gutta-percha was used with lateral condensation technique for obturation of all canals. Periapical radiography and cone beam computed tomography (TCFC) were obtained to verify procedural errors occurred during the preparation of root canals. Two examiners evaluated all images for determining the presence or absence of instrument fracture, root perforation (cervical, middle or apical) and deviation original path of the root canal (apical transport). The data were statistically analyzed employing the Chi-square test. The significance level was 5%. The rate of fractured instruments showed no significant differences in the level of experience of operators (p = 1.000). Root perforations and transport apical occurred more frequently in the group of students, without significant differences. While there have been some procedural errors during root canal preparation with experienced and inexperienced operators, the results suggest that the introduction of tools of nickel-titanium engine-driven education
Desajuste Marginal de Infra-estruturas metálicas de próteses fixas sobre implantes considerando tipos de pilares, materiais e solda a laser
(Universidade Federal de Goiás, 2005-03-24) PEREIRA, Richard Esteves; GUILHERME, Aderico Santana; http://lattes.cnpq.br/8753467344512117
The adaptation precision of metallic structures to implant abutments is a very questionable subject and the scientific literature lacks about the alloy that shows an adaptation closer to the ideal. This study had the proposal of: evaluating the vertical marginal misfit levels (in μm) using a digital microscope of one-piece and after laser welding metallic structures of total fixed implant supported prosthesis casted in Nickel-Chrome, Nickel-Chrome-Titanium-Molibidenium and Palladium-Silver alloys and commercially pure Titanium, over two different kinds of abutments and, also, associate the misfit results observed at the one-piece structures phase with the data obtained after the laser welding treatment. After the fabrication of two master models, 40 pre-fabricated copings for both Estheticone and Micro-Unit type abutments were used at the survey. Eight metallic structures were casted with Ni-Cr, Ni-Cr-Ti-Mo, Pd-Ag and Ti-c.p., being two structures for each alloy. The vertical misfit values concerning the relation of the metallic structures and implant abutments from all alloys and on both stages one-piece and after laser welding were tabulated and then submitted to statistical tests. The values were exposed to the ANOVA and the significant statistic means were compared by the Tukey test considering a 5% significance value (p<0.05), as well as the standard deviation. The results evidenced that the one-piece structures showed misfit, but the mean values did not present statistic significant differences. The material (alloys) analysis showed that the Ti-c.p. did not show discrepant mean values, but the same did not occur with the other alloys. The comparison between all alloys showed no significant statistical differences, and, the Pd-Ag alloy (control group) showed the higher misfit mean values at the one-piece phase. The relation between the one-piece and after laser welding phases showed the presence of statistic significant values, based on the mean values (onepiece= 0.0953 μm / laser welding=0.0452 μm) and the marginal vertical misfit after laser welding appeared significantly decreased.
Ocorrência de anormalidades nos seios maxilares detectadas por meio da tomografia computadorizada por feixe cônico (TCFC) em pacientes assintomáticos
(Universidade Federal de Goiás, 2011-03-18) REGE, Inara Carneiro Costa; LELES, Claudio Rodrigues; http://lattes.cnpq.br/6740286066154410; MENDONÇA, Elismauro Francisco de; http://lattes.cnpq.br/2305019128015847
The use of cone beam computed tomography exam (CBCT) has increased greatly in recent years in dentistry, so there is much discussion about the role of the dentist in evaluating the anatomical structures near the maxillo-mandibular. Currently we do not know the occurrence of abnormalities in the maxillary sinuses in a large sample of CBCT examinations of dental patients with different indications. The aim of this study was 1-to investigate the occurrence of maxillary sinus abnormalities using cone beam computed tomography (CBCT) exams of asymptomatic patients, 2- identify the frequency, type and location of these findings, and 3- its association with the proximity of periapical lesions and inflammatory changes in the maxillary sinus.1113 CBCT exams were evaluated by two examiners to identify the presence or absence of abnormalities of the maxillary sinus. Cases with abnormalities were reevaluated for identification of the type of the abnormality and location within the sinus. The presence and proximity of periapical lesions in the upper posterior teeth to the lower sinus wall were recorded. Data were analyzed using descriptive statistics and chi-square test. Inter-rater agreement was calculated using Kappa statistics. Abnormalities were diagnosed in 760 (68.2%) cases (kappa coefficient 0.83). There was a significant difference between genders, showing greater occurrence in males (p<0.001). No difference in the occurrence of abnormalities was observed regarding age groups (p>0.05). Mucosal thickening was the most prevalent abnormality (66%), followed by retention cyst (10.1%) and opacification (7.8%). The most frequent location of sinusal abnormalities were in the inferior wall (46.2%), anterior (29%), medial(25.7%) and lateral wall (21.5%). No association between the proximity of periapical lesion and the presence and type of inflammatory abnormalities was observed (p=0.124). The occurrence of abnormalities in maxillary sinus of asymptomatic was considered high. These findings emphasize the importance of a comprehensive interpretation by the dentomaxillofacial radiologist of all volume of CBCT images, including the entire maxillary sinus as part of the imaging exam of routine patients.
Avaliação da infiltração microbiana na interface implante-abutment em conexões tipo hexágono interno e cone-morse de implantes osseointegráveis
(Universidade Federal de Goiás, 2007-09-28) SANTANA, Washington Macedo de; PIMENTA, Fabiana Cristina; http://lattes.cnpq.br/2230554075502158; GUILHERME, Aderico Santana; http://lattes.cnpq.br/8753467344512117
The scientific literature has reported that dental implants can be affected by the oral microorganisms through the formation of a bacterial biofilm. The region most affected is the connection between the implant platform and the prosthetic abutment, particularly in implants with an external connection. Therefore, the region of the implant/abutment connection can participate in the development of peri-mucositis or peri-implantitis. They propose that these implant/abutment connections known as morse taper provide an effective seal against microorganisms. Thus the objective of this research was to evaluate the microleakage on the implant/abutment interface of internal hex and morse taper prosthetic connections. Thirty five (35) implants were selected and divided into seven (7) groups (5 groups of implants from Brazilian manufacturers and 2 groups of implants manufactured abroad). The tested implants were Straumann (Straumann AG® / Switzerland), Ankylos (Dentsply-Friadent® / Germany), AR Morse (Conexão/Sistema de Prótese® São Paulo-SP), Titamax CM (Neodent® /Curitiba-PR), Titamax II Plus (Neodent®/Curitiba-PR), Stronger (Sin/Sistema Nacional de Implante® São Paulo - SP) e Titanium Fix CM (AS Technology / São José dos Campos-SP). For the microbiological test the bacterium Enterococus faecalis (ATCC 29212) was selected. This bacterium was inoculated in the interior aspect of the implant followed by immediate installation and final torque (N/cm) of the prosthetic abutment. The implant/abutment set up was then placed in a Brain Heart Infusion broth (BHI) and incubated in this broth for 14 days. During this period, the cloudiness of the broth was evaluated at days 7 and 14. The data were statistically analyzed by the Kruskal Wallis method. The results demonstrated that all samples from both Ankylos and Neodent CM groups did not present microleakage. Although 20% of samples from Conexao AR Morse group presented microleakage, there was no significant statistical difference when compared to the former two groups. Furthermore, all samples from Straumann,Titanium Fix CM, Neodent Titamax II Plus, and SIN Strong groups presented microleakage after 14 days of culture (p=0.05), though correlation analysis among these samples did not reveal significant statistical differences.
Uso do laser de baixa intensidade (GaAlAs) na prevenção de mucosite bucal em pacientes submetidos a transplante de medula óssea
(Universidade Federal de Goiás, 2006-01-13) SILVA, Geisa Badauy Lauria; SILVA, Maria Alves Garcia Santos; http://lattes.cnpq.br/8760691456576488
Oral mucositis is one of the most debilitating complications in patients undergoing bone marrow transplants, occurring 50 to100% in these patients. The oral mucositis treatment and prevention is not completely defined, although the low intensity laser is widely used. The aim of the current study was to investigate the use of low intensity laser (GaAlAs) in the prevention of oral mucositis induced by conditioning regimen in patients undergoing bone marrow transplants. The study was a clinical trial and a total of 42 subjects undergoing allogenic and autologus bone marrow transplant at Araujo Jorge Cancer Hospital of the Combact Cancer Association of Goiás were enrolled. All patients received a high dose chemotherapy conditioning regimen associated or not with total body radiation. The Experimental Group received the hospital protocol of oral hygiene and preventive irradiation of low level laser (660nm) on day -4 (D-4) through post-transplant day 4 (D+4). The Control Group received just the hospital protocol of oral hygiene. Oral mucositis degree was evaluated daily according to the World Health Organization Scale (WHO) on day -2 until the wound healing. The Group which low level laser treatment was performed prophylactically, 57,1% of patients were free from mucositis and no one showed mucositis degree III and IV. The difference between both Groups related to the occurrence (p<0,001) and severity (p<0,008) of oral mucositis were statistically meanful. It was concluded that the low level laser treatment, prophylactically reduces the occurrence and severity of oral mucositis
Avaliação do processo de raparo de lesões periopicais pós-tratamento endodôntico por meio de subtração digital radiográfica
(Universidade Federal de Goiás, 2006-11-30) SILVA, Janaína Benfica e; ALENCAR, Ana Helena Gonçalves de; http://lattes.cnpq.br/2039898015468283; MENDONÇA, Elismauro Francisco de; http://lattes.cnpq.br/2305019128015847
Control of the process of repair or progression of periapical lesions after endodontic treatment is monitored by conventional or digital radiography. In this research digital subtraction radiography (DSR) was used that uses the subtraction of images longitudinally, in which the change in the alveolar bone is visualized against a uniform gray background. The objectives of this study were: (1) to evaluate the repair process of periapical lesions after endodontic treatment by using DSR; (2) to quantify by means of point/pixel (picture element), area (histogram) and linear measures (profile line), the gain or loss of mineral density in the area of the lesion, using the average of the pixel values; (3) to compare the diagnostic information, suggestive of the repair process, obtained through a subjective evaluation of DSR with a conventional radiographic evaluation and digitalized image and (4) to evaluate the contribution of DSR to an early identification of the repair of periapical lesions after endodontic treatment. The sample consisted of twelve patients with a total of seventeen periapical lesions. The x-rays were digitalized and submitted to DSR using DSR software. The pixel values of the subtracted images were determined by using Image Tool software. Both the conventional x-rays as well as the digitalized and subtracted images were qualitatively evaluated. The results showed a gain in mineral density with a meandp of 133.495.17, 130.275.77 and 129.414.46 for the points/pixel, histogram and profile line tools, respectively. In the evaluation of numerical gain Pearson s Coefficient of Correlation (r) presented these values: mean of points/histogram = 0.746; mean of points/profile line = 0.724 and histogram/profile line = 0.860. When the numerical values were transformed into percentile gain meandp of 0.674.01, 1.214.33 and 1.163.36 were obtained for the points/pixels, histogram and profile line tools, respectively. In the evaluation of the percentile gain Spearman s Coefficient of Correlation (rs) showed the following values: mean of points/histogram = 0.697; mean of the points/profile line = 0.646 and histogram/profile line = 0.844. In the qualitative analysis, the frequency of success in the ordering of the correct sequence of the repair process using conventional radiography, digitalized image and DSR was 37.3%, 31.4% and 31.4%, respectively. One concluded, therefore, that: (1) the process of repair of periapical lesions after endodontic treatment can be evaluated quantitatively by means of longitudinal analysis using DSR; (2) any one of the three tools can be used to quantify the repair, considering that correlation exists between the time of repair and the increase of the value of pixel; (3) the comparative evaluation between the subjective methods using conventional radiography, digitalized image and SDR, it showed that all had been capable to evidence the process of repair of periapical lesions from the first radiography (15 days), not having difference between them and (4) the quantitative evaluation by SDR obtained to after evidence the beginning of the repair with 15 days the beginning of the endodontic treatment, even so this repair was really effective from 105 days after the beginning of the endodontic treatment.
Neoplasias malignas em cavidade orbitária e reabilitação pós-cirúrgica em um hospital brasileiro de oncologia - estudo retrospectivo de 12 anos
(Universidade Federal de Goiás, 2010-08-06) SIRIANNI, Daniela; MENDONÇA, Elismauro Francisco de; http://lattes.cnpq.br/2305019128015847
Malignant tumors in the orbital cavity often require surgical treatment, however, few studies recording the prevalence of tumors in the orbit and post-surgical rehabilitation through maxillofacial prosthetics. The aim of this study was to investigate the prevalence of malignant tumors in the orbital cavity, employed as the surgical treatment and prosthetic rehabilitation after surgery. A retrospective convenience sample was selected from 269 charts of patients treated at Hospital Araújo Jorge (Goiânia, Goiás, Brazil), regional referral center for cancer treatment and supported by the National Health System, from 1998 to 2009. Data concerning the clinical and pathological, psychological support, rehabilitation, prosthetics and clinical outcome were investigated. Descriptive statistical analysis revealed that the age group ranged from 1 to 92 years, mean 43.5 years, 50.2% of female patients. Tumors were more prevalent basal cell carcinoma (58%), retinoblastoma (17.1%), squamous cell carcinoma of the conjunctiva (7.1%), malignant melanoma (6.7%) and rhabdomyosarcoma (4.5%). Of the total, 250 patients (92.3%) underwent surgery by exenteration (78%) or enucleation (21.6%). Variables associated with the rehabilitation aesthetic eye were age (p <0.001) and type of surgery (p <0.001). It follows then that there are low rates of prosthetic care and psychological care offered to patients and that the process was influenced by the esthetic rehabilitative patient's young age and in cases of surgical enucleation of the eyeball
Retenção de grampos cirucenferenciais associados a retentores intra-radiculares com encaixe era utilizados em overdentures parciais removíveis
(Universidade Federal de Goiás, 2008-07-18) SOUZA, José Everaldo de Aquino; ZAVANELLI, Ricardo Alexandre; http://lattes.cnpq.br/6610989896574204
The overdentures can be defined as total or partial removable dentures that cover root or osseo integrated implants rehabilitating the whole dentition. The mechanical retention in the removable partial overdentures (RPOs) is obtained through the use of cast clasps and attachments. This biomechanical principle has a great importance, since is inwardly associated with long term behavior and clinical performance of prosthesis and consequently, with comfort and satisfaction of the patients. So, the aim of this study was to assess the retention of metallic framework with simple circumferential claps associated intraradicular retainer with attachment type ERA (Extra coronal Resilient Attachment, Sterngold Implamed, Attleboro, EUA) in function of the metals based cobalt-chromium alloy (Co-Cr), titanium commercially pure (Ti cp) and nickel-chromium with titanium alloy (Ni-Cr with Ti), of the retentive undercuts of 0,25mm and 0,75mm and in function of the time of use in each simulated period (initial, 6 months, 1, 2, 3, 4 e 5 years). Through of metallic matrices representing a partially edentulous mandibular right hemi-arch segment constituted by the crown of the first molar, root of the inferior canine and with the absent of the premolars, were made 60 metallic frameworks being obtained 03 groups of each metal and subgroups representative of the 0,25mm and 0,75mm retentive undercuts of the circumferential clasp (totalizing 10 samples in each subgroup). Acrylic denture bases were constructed on the denture space and on the canine root that anchored the attachments and these received retentive capsules in the gray color of the system. Previously the mechanic tests, radiographic exams of the Ti cp frameworks were realized with the aim of detecting possible casting defects that could avert the posterior use. Next, the samples were mechanically tested simulating the insertion and removal of the framework using the testing apparatus designed at the Ribeirão Preto School of Dentistry (Testing apparatus, São Paulo University, Ribeirão Preto, Brazil), representing 5 years of simulated used. To simulate the intraoral conditions and realize the tests, a gadget fulfilled with artificial saliva was adapted in the testing apparatus. The retentive force data were recorded and submitted linear regression analysis and analysis of variance (ANOVA) to gauge a presence or not of significant differences and applied the Tukey complementary test 5% to comparison of the differences between the groups and subgroups. The groups of Ni-Cr with Ti and Co-Cr samples obtained most retentive mean with significant differences to group of Ti cp samples that obtained least retentive mean in every periods of time analyzed. To groups Ni-Cr with Ti and Co-Cr samples there was not significant difference of retention between the times analyzed free-standing of retentive undercuts (p > 0,05). In the group Ti cp samples there was significant difference of retention between the times analyzed just to subgroup samples with 0,75mm undercuts (p < 0,05). The Ni-Cr with Ti and Co-Cr samples with 0,75mm undercuts presented the most retentive mean and the Co-Cr samples with 0,25mm undercuts presented retention mean intermediate between biomechanical design in every periods of time analyzed. The Ti cp samples with 0,25mm undercuts presented the least retentive mean until second year of the analyze and the Ti cp samples with 0,75mm undercuts presented the least retentive mean of third until fifth year of the analyse. The circumferential claps casting in Ti cp used in 0,75mm undercuts have potential risk of fractures, mainly after the 2o year of use
Detecção de HPV e avaliação do índice de proliferação celular entre carcinomas espinocelulares e carcinomas verrucosos de boca
(Universidade Federal de Goiás, 2006-11-27) SPÍNDULA FILHO, José Vieira de; CRUZ, Aparecido Divino da; http://lattes.cnpq.br/7868817504129985; MENDONÇA, Elismauro Francisco de; http://lattes.cnpq.br/2305019128015847
Squamous cell carcinoma (SCC) is the most common malignant neoplasm of the bucal cavity, and one of its variants is verrucous carcinoma (VC), of low degree malignancy. The diagnosis of VC is difficult from the clinical as well as from the histopathological point of view, and an effective diagnosis is vital when deciding on the treatment and prognosis of this tumor. The aim of this research was to evaluate cell proliferation and investigate the presence of HPV in spindle cell carcinoma of the mouth so as to check for possible differences in the aetiopathogenesis and biological behavior of these lesions. Forty-seven samples were selected and divided as follows: 39 SCCs, 8 VCs and 9 control (CT). Cell proliferation was qualitatively evaluated according to the location of the expression of the immunomarker in the cell and epithelium layers and by quantitatively considering the percentage of positive cells expressed. The analysis of HPV+ carcinomas was undertaken by means of the polymerase chain reaction (PCR), having GP5+/6+ as primers for identification of the virus. The qualitative analysis showed that the immunomarking in the VC as well as in the control group was concentrated mainly in the basal and parabasal layers and the counting of the positive cells at the base of the epithelium showed a significant statistical difference in the expressions of all three markers (p<0,05). The quantitative analysis of the cell proliferation markers was calculated by means of the Mann-Whitney and Kruskal Wallis tests and through the Pearson and Spermans correlation. They pointed to differences between the SCC and VC groups for the PCNA and cyclin B1 markers (p<0,05). On considering the three groups, it was proved that there was a positive correlation between Ki67 and the cyclin B1 (r=0,56) but not between the PCNA and the Ki67. The PCNA immunomarking was greater in the control group (average=100%), and the Ki67 showed itself to be effective as a proliferation cell marker although it showed no significant difference between the carcinoma variants. Whereas the cyclin B1 showed a significant difference in the comparison between the SCC and the VC groups (p<0,05), and a positive correlation to the extent that the histological grading of the malignancy (WHO model) of the carcinomas increased (r=0,44). All tumor samples were negative for HPV. Although the lesions showed different biological behaviors, the cell proliferation index in both types of mouth carcinoma was higher than in the control group, as shown by the analysis of the Ki67 and cyclin B1 markers. On considering the total sample of carcinomas, independently of the tumor variety, cyclin B1 showed a positive correlation with the histological degree of malignancy according to WHO. There is a need for further study to be carried out in the field of cell proliferation and detection of HPV especially with regard to VC, because it is a rare variant of SCC.

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