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Item Técnica laparoscópica versus técnica aberta para adrenalectomia experimental em suínos(Universidade Federal de Goiás, 2009-12-22) GAMA FILHO, José Belarmino da; SILVA, Luiz Antônio Franco da; http://lattes.cnpq.br/0446055905975647; PAULO, Neusa Margarida; http://lattes.cnpq.br/7949273598509043Adrenalectomy is a highly complex surgical procedure. In order to perform it, surgeons must have a profound knowledge of the anatomophysiologic aspects of the adrenal glands, especially their vascular diversity, as well as full understanding of diagnostic means so as to properly identify their diseases. Open adrenalectomy is the most widely used method in veterinary medicine, while laparoscopic adrenalectomy usually is the method of choice in human medicine. Hyperadrenocorticism, whether hypophysis-dependent or not, is the most the most common adrenal disease. Treatment involves stopping the growth of tumors either surgically or chemically. Treatment of choice will depend on tumor functionality, type and size, as well as on its image. The swine model has proven adequate for surgical procedures, since it possesses standardized experimentation protocols and physiological parameters. Among the main benefits of laparoscopic adrenalectomy versus open adrenalectomy is rapid recovery and diminished hospitalization time. Laparoscopic adrenalectomy is the procedure of choice in human medicine, and it is nowadays considered to be the gold standard. In veterinary medicine more research is needed so as to better establish its advantages over open adrenalectomy. In this study open adrenalectomy was compared to laparoscopic adrenalectomy. 32 swines, divided into four groups of eight animals each, underwent surgery; being it that one group underwent open and the other laparoscopic adrenalectomy, with their respective control groups (sham). Parameters such as surgical time, body temperature, haematocrit, surgical intercurrences and XXXXX, as well as physiological, hormonal and metabolic responses were evaluated in young swines, both in open and laparoscopic adrenalectomy. There were no significant differences in surgical times. Most frequent intercurrences were accidents with intestinal loops, lesions to adrenal vessels and renal haematoma. Blood losses were not significant and, even though there was hypothermia it did not lead to any unfavorable clinical outcome. Deambulation time was longer for the open adrenalectomy group, although the difference was not significant. Significant differences were found in leucometry values of the laparoscopic sham group, which were higher when compared to laparoscopic groups; SpO2 of the G3 group was lower than that of the other groups, and PCR of the laparoscopic groups were lower postoperatively. There were no significant differences in mean blood pressure in all of four groups. Laparoscopy is a reliable technique for experimental adrenalectomy in swines and can be used as a reference for surgical treatment of adrenal diseases in other animal species. Metabolic parameters did not show significant differences. These results indicated that the laparoscopic technique is beneficial over open surgery, and that it can be considered a safe procedure for other species. Adrenalectomy is a highly complex surgical procedure. In order to perform it, surgeons must have a profound knowledge of the anatomophysiologic aspects of the adrenal glands, especially their vascular diversity, as well as full understanding of diagnostic means so as to properly identify their diseases. Open adrenalectomy is the most widely used method in veterinary medicine, while laparoscopic adrenalectomy usually is the method of choice in human medicine. Hyperadrenocorticism, whether hypophysis-dependent or not, is the most the most common adrenal disease. Treatment involves stopping the growth of tumors either surgically or chemically. Treatment of choice will depend on tumor functionality, type and size, as well as on its image. The swine model has proven adequate for surgical procedures, since it possesses standardized experimentation protocols and physiological parameters. Among the main benefits of laparoscopic adrenalectomy versus open adrenalectomy is rapid recovery and diminished hospitalization time. Laparoscopic adrenalectomy is the procedure of choice in human medicine, and it is nowadays considered to be the gold standard. In veterinary medicine more research is needed so as to better establish its advantages over open adrenalectomy. In this study open adrenalectomy was compared to laparoscopic adrenalectomy. 32 swines, divided into four groups of eight animals each, underwent surgery; being it that one group underwent open and the other laparoscopic adrenalectomy, with their respective control groups (sham). Parameters such as surgical time, body temperature, haematocrit, surgical intercurrences and XXXXX, as well as physiological, hormonal and metabolic responses were evaluated in young swines, both in open and laparoscopic adrenalectomy. There were no significant differences in surgical times. Most frequent intercurrences were accidents with intestinal loops, lesions to adrenal vessels and renal haematoma. Blood losses were not significant and, even though there was hypothermia it did not lead to any unfavorable clinical outcome. Deambulation time was longer for the open adrenalectomy group, although the difference was not significant. Significant differences were found in leucometry values of the laparoscopic sham group, which were higher when compared to laparoscopic groups; SpO2 of the G3 group was lower than that of the other groups, and PCR of the laparoscopic groups were lower postoperatively. There were no significant differences in mean blood pressure in all of four groups. Laparoscopy is a reliable technique for experimental adrenalectomy in swines and can be used as a reference for surgical treatment of adrenal diseases in other animal species. Metabolic parameters did not show significant differences. These results indicated that the laparoscopic technique is beneficial over open surgery, and that it can be considered a safe procedure for other species.