Investigação da infecção pelo vírus da hepatite C em indivíduos em situação de rua albergados em Goiânia, Goiás: prevalência e fatores associados
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2017-04-25
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Universidade Federal de Goiás
Resumo
Homeless people are at high risk for parental and sexual infections, such as hepatitis C virus
(HCV) infection. This study aimed to investigate the epidemiological profile of the infection
caused by the hepatitis C virus in homeless people housed in Goiânia, Goiás. This is an
observational, cross-sectional and analytical investigation. Between August 2014 and July
2015, 353 homeless people hosted in the only public institution of the state of Goiás were
interviewed about sociodemographic characteristics, knowledge and risk factors for hepatitis
C, and subsequently tested for the detection of the marker HCV by immunochromatographic
test (rapid test) and ELISA. In addition, monitoring of individuals reagentes for HCV was
conducted through the information systems of the Unified Health System. The Poisson
regression analysis was used to verify the risk factors associated with exposure to HCV with
robust variance for the calculation of prevalence ratio (PR). The investigated were mostly
male (81.3%), aged between 18 and 45 years (73.62%), singles (59.8%), with no income
(35.7), with 5 to 9 years of study (53.3%) and self-reported brown color (61.1%). The study
evidenced a knowledge deficit of the homeless people investigated in relation to the HCV
transmission. The rapid test used in this study had a high index of agreement with the ELISA,
whose sensitivity and specificity was 91.7% and 99.7%, respectively. The overall prevalence
of HCV in the homeless people housed was 3.4% (95% CI: 1.9-5.8). It was noted that age
(RP: 1.05, 95% CI: 1.02-1.09), be natural from the Southeast region (RP: 2.27, 95% CI:
1.03-5.02), overnight experience in the street (RP: 2.78, 95% CI: 1.11-6.91) and the use of
injectable drugs (UID) (PR: 16.59, 95% CI: 4.23-65.09) were statistically associated with HCV
infection. Of the 12 housed positive for HCV, only two sought treatment, but there was no
adhesion, and another two others evolved to death as a consequence of hepatic cirrhosis due
to hepatitis C. The results of the study ratify the extreme condition of homeless people and
the increased risk of acquiring and disseminating the hepatitis C virus. Therefore, to prevent
and / or minimize risk behaviors for HCV, it is necessary behavioral and structural
interventions with combined strategies, such as health education and counseling, permanent
education, provision of rapid testing and barrier methods (condom), multidisciplinary
treatment, strengthening the strategy of damage reduction, evaluation of policies for
homeless people, solidifying the social care equipment provided to this group, such as shelters
and access to the services that comprise the health care network.
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SOUZA, Jéssyca Pereira e. Investigação da infecção pelo vírus da hepatite C em indivíduos em situação de rua albergados em Goiânia, Goiás: prevalência e fatores associados. 2017. 110 f. Dissertação (Mestrado em Enfermagem) - Universidade Federal de Goiás, Goiânia, 2017.