Meningoencefalite: dados clínicos, bacteriológicos e terapêuticos em 351 casos
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1973-06
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Ruy de Souza Lino Junior
Resumo
351 cases of menmgoencephalitis are
presented. The aim of thís paper is
to show the most frcquent etiologies
and the therapeutic results obtained
with an association of Penicilin G, Sulfadiazine
and Chloramphenmoi and
with a hroad-spectrum *emi-*ynthelie
penicillin. A syndromic classificatioa
of the neurological pícture ia relation to the duratíon of the disease before
hospitalization and the clinicai evolution
is presented. The meningoencephalites
contributed with 21,26% of
the hospiatl casuistic: acute bacterial
meningoencephalitis o c c ur r 'e d in
48,14% of the total; asseptic (virai
and undetermined) in 46,72% and tuberculous
in 5,09%. In the acute bacterial
group, meningococcus was responsible
for 56,1% of the cases, staphylococcus
for 14,47%, pneumococcus
for 11,34%, Pfeiffer's bacillus
for 5,46%. Proteus, Pseudomonas,
Klebsiella and streptococci occurred
in less than 8% of the bacterial group.
A puré meningeal syndrome was observed
more f requently in patíents with
less than two days of disease who
presented a more favourable evolution
than the patíents with signs of
encephalic and medullary involvelment.
Hospital mortality in the patients
treated with a combination of
penicillin G — sulfa — chloramphenicol,
in 79 cases, was 25,32%; with
epicillin in 36 cases was 16,66% and
with ampicillin in 54 cases, 14,82%.
It is concluded that meningococcus is
the most important etiologíc agent of
meningoencephalitis in Goiás, that a
single ínitial therapy with broad-spectrum
penicillin is superior thant the
association of penicillin G — sulfadíazie
— chloramphenicol and that a
syndromic classification of the neurological
picture ís useful for the evaluation
of prognosis.
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ALMEIDA NETTO, Joaquim Caetano de; REIS, Cleomenes; VIEIRA FILHO, José; DINIZ, Mário; ARAÚJO, Lélio Leonardo; KOLEILAT, Mohamad Nader M. Meningoencefalite: dados clínicos, bacteriológicos e terapêuticos em 351 casos. Revista de Patologia Tropical, Goiânia, v. 2, n. 2, p. 189- 205, abr./jun. 1973. Disponível em: < https://www.revistas.ufg.br/iptsp/article/view/22736/13529>.